Alexandre Pawlik

Centre National de la Recherche Scientifique — France

Medicine · Health Sciences

21h-index2.0kcitations58works2.42yr avg
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Research Topics

Tuberculosis Research and Epidemiology(30), Mycobacterium research and diagnosis(24), Antibiotic Resistance in Bacteria(8), Immunotherapy and Immune Responses(7), Monoclonal and Polyclonal Antibodies Research(4)

Publications58 total

Improved immune responses and tuberculosis protection by aerosol vaccination with recombinant BCG expressing ESX-1 from Mycobacterium marinum
PLoS Pathogens·2026Open Access
Improved Immune Responses and Tuberculosis Protection by Aerosol Vaccination with recombinant BCG expressing ESX-1 from <i>Mycobacterium marinum</i>
2025Open Access
LB-006 Final results – EVAQ study of the Q revascularization system in acute ischemic stroke
2024Open Access
Genomic and phenotypic characterization of <i>Mycobacterium tuberculosis’</i> closest-related non-tuberculous mycobacteria
Microbiology Spectrum·2024· 7 citedOpen Access
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection
PLoS Biology·2024· 5 citedOpen Access
An oxadiazole-based compound potentiates anti-tuberculosis treatment by increasing host resistance via zinc poisoning
2023Open Access
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli
PLoS Pathogens·2023· 15 citedOpen Access
A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4+ T-cell immunity
Mucosal Immunology·2022· 11 citedOpen Access
A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity
Cell Reports·2022· 15 citedOpen Access
Author response: De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis
2021· 1 citedOpen Access
Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli
Nature Microbiology·2021· 23 cited
<i>De novo</i> synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for <i>Mycobacterium tuberculosis</i>
2021Open Access
Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts
Microbial Genomics·2021· 24 citedOpen Access
TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages
Nature Communications·2020· 112 citedOpen Access
Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages
PLoS Pathogens·2019· 69 citedOpen Access
Lsr2 Is an Important Determinant of Intracellular Growth and Virulence in Mycobacterium abscessus
Frontiers in Microbiology·2019· 34 citedOpen Access
From environmental bacteria to obligate human pathogen: adaptations associated with the emergence of tuberculosis bacilli
HAL (Le Centre pour la Communication Scientifique Directe)·2019
Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages
2019· 16 cited
Identification of Virulence Markers of &lt;em&gt;Mycobacterium abscessus&lt;/em&gt; for Intracellular Replication in Phagocytes
Journal of Visualized Experiments·2018· 5 citedOpen Access
Identification of Virulence Markers of &lt;em&gt;Mycobacterium abscessus&lt;/em&gt; for Intracellular Replication in Phagocytes
Journal of Visualized Experiments·2018· 1 cited
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Frequent Co-authors

Roland Brosch(24), Wafa Frigui(20), Laleh Majlessi(13), Fadel Sayes(12), Jean‐Louis Herrmann(9), Laurence Ma(8), Christiane Bouchier(8), Mickael Orgeur(7), G. Sender(7), Wladimir Malaga(6), Christophe Guilhot(6), Vincent Le Moigne(5), Crommelynck Samuel(5), Catherine Fayolle(5), J. Oprządek(5), Brosch Roland(5), Philip Supply(4), Eva C. Boritsch(4), Mamadou Daffé(4), Jean‐Yves Coppée(4)