Songsong Dan

State Key Laboratory of Diagnosis and Treatment of Infectious Diseases

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index324citations16works2.02yr avg
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Research Topics

Pluripotent Stem Cells Research(9), CRISPR and Genetic Engineering(9), Renal and related cancers(4), RNA Research and Splicing(3), Epigenetics and DNA Methylation(2)

Publications16 total

ATR regulates OCT4 phosphorylation and safeguards human naïve pluripotency
Scientific Reports·2025· 1 citedOpen Access
OCT4 translationally promotes AKT signaling as an RNA-binding protein in stressed pluripotent stem cells
Stem Cell Research & Therapy·2025· 3 citedOpen Access
Identification of VPS34-PI(3)P-FEN1-mediated DNA repair pathway as a potential drug target to overcome chemoresistance
Biochemical and Biophysical Research Communications·2023· 2 cited
Translational and post-translational control of human naïve versus primed pluripotency
iScience·2021· 13 citedOpen Access
DNA repair proteins cooperate with SOX2 in regulating the transition of human embryonic stem cells to neural progenitor cells
Biochemical and Biophysical Research Communications·2021· 5 citedOpen Access
LSD1-mediated demethylation of OCT4 safeguards pluripotent stem cells by maintaining the transcription of PORE-motif-containing genes
Scientific Reports·2021· 7 citedOpen Access
Combined inhibition of JAK1/2 and DNMT1 by newly identified small-molecule compounds synergistically suppresses the survival and proliferation of cervical cancer cells
Cell Death and Disease·2020· 69 citedOpen Access
The OCT4-RNA Interactome in Pluripotent Stem Cells Reveals Direct Translational Regulation of the AKT-Pathway Genes by OCT4
SSRN Electronic Journal·2020Open Access
Identification of a Novel Oral Small-Molecule JAK1/2 Inhibitor and Its Potent Synergistic Drug Combinations Against Cervical Cancer
SSRN Electronic Journal·2019Open Access
Endogenous authentic OCT4A proteins directly regulate FOS/AP-1 transcription in somatic cancer cells
Cell Death and Disease·2018· 24 citedOpen Access
Site-specific Disruption of the Oct4/Sox2 Protein Interaction Reveals Coordinated Mesendodermal Differentiation and the Epithelial-Mesenchymal Transition
Journal of Biological Chemistry·2016· 39 citedOpen Access
Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells
Nature Communications·2015· 112 citedOpen Access
A cell-free system toward deciphering the post-translational modification barcodes of Oct4 in different cellular contexts
Biochemical and Biophysical Research Communications·2014· 13 citedOpen Access
14‐3‐3ζ Reduces DNA Damage by Interacting With and Stabilizing Proliferating Cell Nuclear Antigen
Journal of Cellular Biochemistry·2014· 19 cited
Akt–Oct4 regulatory circuit in pluripotent stem cells
Chinese Science Bulletin·2014· 17 cited
88 In silico and biological evaluation of correlation between efficacy of PI3K inhibitors with the activation status of signaling pathways in a panel of JFCR39 human cancer cell lines
European Journal of Cancer Supplements·2010

Frequent Co-authors

Bo Kang(13), Yingjie Wang(10), Chen Cheng(9), Shiqi She(8), Wenjie Chen(8), Xinyu Chen(7), Yanwen Zhou(4), Jingchao Li(4), Jianwen Hu(4), Xiaobing Zhang(3), Xiaotao Duan(3), Xiao‐Bing Zhang(3), Yisha Wang(3), Qingyi Cao(3), Jie Cheng(2), Wenxin Li(2), Hongcui Cao(2), Chenggang Zhu(2), Qingwei Zhao(2), Lanjuan Li(2)