Michel Desjardins

Université de Montréal — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

51h-index12.1kcitations236works0.62yr avg
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Research Topics

Cellular transport and secretion(24), Autophagy in Disease and Therapy(18), Biblical Studies and Interpretation(17), Erythrocyte Function and Pathophysiology(15), Historical, Religious, and Philosophical Studies(11)

Publications236 total

Author Reply to Peer Reviews of LRRK2G2019S interferes with NCOA4 trafficking in response to iron overload leading to oxidative stress and ferroptotic cell death.
2026
Poster Session I - A30 INVESTIGATING THE IMPACT OF PARKINSON’S DISEASE-ASSOCIATED GENE <i>PINK1</i> ON INTESTINAL HOMEOSTASIS AND RESPONSE TO INFECTION
Journal of the Canadian Association of Gastroenterology·2026Open Access
Modeling gene-environment interactions in Parkinson’s Disease: Helicobacter pylori induces CD8 T cell associated motor phenotype in PINK1-/- mice 9116
The Journal of Immunology·2025Open Access
The Parkinson’s Disease-associated mutation LRRK2 G2019S impacts neutrophil effector functions and the response to intestinal infection in mice 9106
The Journal of Immunology·2025Open Access
MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death
Nature Cell Biology·2025· 5 citedOpen Access
Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis
npj Parkinson s Disease·2025Open Access
LRRK2G2019S acts as a dominant interfering mutant in the context of iron overload
2025Open Access
A150 THE PARKINSON’S DISEASE-ASSOCIATED MUTATION LRRK2 G2019S INCITES NEUTROPHILIC INFLAMMATION AND INCREASED TISSUE DAMAGE IN A MOUSE MODEL OF INFECTIOUS COLITIS.
Journal of the Canadian Association of Gastroenterology·2025Open Access
A14 INVESTIGATING THE IMPACT OF PARKINSON’S DISEASE-ASSOCIATED GENE <i>PINK1</i> ON INTESTINAL HOMEOSTASIS AND RESPONSE TO INFECTION
Journal of the Canadian Association of Gastroenterology·2025Open Access
A single <i>Citrobacter rodentium</i> infection in Pink1 knockout and wild type mice leads to regional blood-brain-barrier perturbation and glial activation without dopamine neuron axon terminal loss
2024Open Access
LRRK2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis
2024· 1 citedOpen Access
Modeling gene-environment interactions in Parkinson’s Disease: <i>Helicobacter pylori</i> infection of <i> Pink1 <sup>−/−</sup> </i> mice induces CD8 T cell-dependent motor and cognitive dysfunction
2024· 2 citedOpen Access
A29 INVESTIGATING THE IMPACT OF PARKINSON’S DISEASE-ASSOCIATED GENES ON INTESTINAL HOMEOSTASIS
Journal of the Canadian Association of Gastroenterology·2024Open Access
Parkinson’s genes orchestrate pyroptosis through selective trafficking of mtDNA to leaky lysosomes
2023· 14 citedOpen Access
Protocols for &amp;#34;Mitochondrial Anchored Protein Ligase MAPL is an inflammatory rheostat that regulates immune signalling and cell death&amp;#34; v1
2023· 1 citedOpen Access
Protocols for &amp;#34;MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death&amp;#34; v2
2023Open Access
LRRK2 regulates the activation of the unfolded protein response and antigen presentation in macrophages during inflammation
2023· 4 citedOpen Access
Discussion
2023
Religious food guidance
Canadian Food Studies / La Revue canadienne des études sur l alimentation·2022Open Access
Understanding Gut Feelings: Transformations in Coping With Inflammatory Bowel Disease Among Young Adults
Qualitative Health Research·2021· 20 citedOpen Access
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Frequent Co-authors

Christiane Rondeau(12), Sophie Duclos(8), Pierre Thibault(8), Étienne Gagnon(7), Annie Laplante(6), Mathieu Houde(5), Albert Descoteaux(5), Magali Chemali(4), Luc English(4), Matthias Trost(4), Jérôme Garin(3), Jean-François Dermine(3), Guillaume Goyette(3), Robert G. Parton(3), Diana Matheoud(3), Stéphane Méresse(3), Jean‐Pierre Gorvel(3), Jonathan Boulais(3), Isabelle Jutras(3), Christina Bell(3)