Kai-Leng Tan

Guangdong University of Technology — China

Medicine · Health Sciences

10h-index460citations18works0.02yr avg
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Research Topics

Down syndrome and intellectual disability research(5), Neuroinflammation and Neurodegeneration Mechanisms(5), Neuroscience and Neuropharmacology Research(3), MicroRNA in disease regulation(2), Immune Response and Inflammation(2)

Publications18 total

Metabolic perspective of astrocyte dysfunction in Alzheimer's disease and type 2 diabetes brains
Biomedicine & Pharmacotherapy·2023· 51 citedOpen Access
Mitochondrial Dysfunction in Down Syndrome: From Pathology to Therapy
Neuroscience·2022· 34 cited
Enhanced Contextual Fear Memory and Elevated Astroglial Glutamate Synthase Activity in Hippocampal CA1 BChE shRNA Knockdown Mice
Frontiers in Psychiatry·2020· 7 citedOpen Access
miR-142-3p Regulates BDNF Expression in Activated Rodent Microglia Through Its Target CAMK2A
Frontiers in Cellular Neuroscience·2020· 40 citedOpen Access
JAK-STAT Signaling Pathway and Gliosis in Neuroinflammatory Diseases
2020· 2 cited
‘Sweeter’ than its name: anti-inflammatory activities of <i>Stevia rebaudiana</i>
All Life·2020· 17 citedOpen Access
The anti-inflammatory potential of STVNa in modulating microglial activation in cerebral ischemia–reperfusion injury
IBRO Reports·2019Open Access
Knockdown of butyrylcholinesterase in the hippocampal ca1 strengthen contextual fear memory
IBRO Reports·2019Open Access
Over-expression of Ifnar1 and the neurogenic-to-gliogenic shift: A potential mechanism in Down syndrome brain
IBRO Reports·2019Open Access
The potential of MLC901 (NeuroAiD II™), a traditional Chinese medicine
Neuroscience Research Notes·2019· 6 citedOpen Access
Disrupted interferon-related molecular networks and the over-expressed Ifnar1 in the brain of adult Ts1Cje mouse model of Down syndrome
Frontiers in Cellular Neuroscience·2016Open Access
Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain
Neural Plasticity·2016· 48 citedOpen Access
Harvesting the maximum length of sciatic nerve from adult mice: a step-by-step approach
BMC Research Notes·2014· 27 citedOpen Access
Transcriptional profiling of the postnatal brain of the Ts1Cje mouse model of Down syndrome
Genomics Data·2014· 4 citedOpen Access
Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks
BMC Genomics·2014· 69 citedOpen Access
MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID, and Fragile X syndrome
Frontiers in Cellular Neuroscience·2013· 45 citedOpen Access
What Does It Take to Synergistically Combine Sub-Potent Natural Products into Drug-Level Potent Combinations?
PLoS ONE·2012· 18 citedOpen Access
Chemopreventive Potential of Annona Muricata L Leaves on Chemically-Induced Skin Papillomagenesis in Mice
Asian Pacific Journal of Cancer Prevention·2012· 92 citedOpen Access

Frequent Co-authors

King‐Hwa Ling(8), Pike-See Cheah(8), Han-Chung Lee(5), Qiwen Tan(4), Chelsee Hewitt(2), Sharmili Vidyadaran(2), Ken Simpson(2), Melanie Pritchard(2), Gordon K. Smyth(2), Tim Thomas(2), Hamish S. Scott(2), Si Chen(2), Zhengdong Lin(2), Wen Tan(2), Sulaiman Hamizah(1), A. H. Roslida(1), O. Fezah(1), Yin Sim Tor(1), Chu-Bing Tan(1), Mei I Lai(1)