Hassan M. Otifi

King Khalid University — Saudi Arabia

Chemistry · Physical Sciences

8h-index334citations31works1.12yr avg
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Research Topics

Synthesis and biological activity(3), Cell death mechanisms and regulation(3), Prostate Cancer Treatment and Research(3), Nigella sativa pharmacological applications(3), Prostate Cancer Diagnosis and Treatment(2)

Publications31 total

Antioxidant activity of 2-mercaptoethanol protects against CD8+ T cell overstimulation or accelerated exhaustion: evidence from an in vitro exhausted CD8+ T model and in vivo adoptive cell transfer
International Immunopharmacology·2026
In-Silico identification and optimization of therapeutic peptides against breast cancer via transcriptomic profiling
Molecular Diversity·2026· 1 cited
ALG3 as a PanCancer Oncogene: Bioinformatics Analysis and Identification ofSmall-Molecule Inhibitors
Anti-Cancer Agents in Medicinal Chemistry·2025
Correction: Oncogenic EME1 promotes tumor progression and immune modulation in human cancers with therapeutic targeting potential
Discover Oncology·2025Open Access
Oncogenic EME1 promotes tumor progression and immune modulation in human cancers with therapeutic targeting potential
Discover Oncology·2025· 1 citedOpen Access
Nepetin attenuates sertraline-induced cardiac dysfunction by modulating notch signaling, oxidative stress, and inflammation: Echocardiographic and histological evidence
Tissue and Cell·2025
Application of Multi-Omics and Chemoinformatics to Analyze Oncogenic Roles and Assess Potential Inhibitors for NCAPG
Journal of Computational Biophysics and Chemistry·2025· 1 cited
Fenthion Triggers Cardiac Dysfunction Through TLR4, HMGB1/RAGE, and NF‐<i>κ</i>B Pathways: An In Vivo and In Silico Assessment
Journal of Applied Toxicology·2025· 1 cited
Syringetin ameliorates thallium sulphate induced renal dysfunction via regulating Nrf2/Keap-1, TLR4/HMGB1/RAGE and NF-κB pathway
Tissue and Cell·2025· 5 cited
Targeting the Inactive Conformation of the Epidermal Growth Factor Receptor Identifies EG31: A Novel Small Molecule Inhibitor Effective Against Normal and 5-Fluorouracil-Resistant Triple Negative Breast Cancer Cells
OncoTargets and Therapy·2025· 1 citedOpen Access
Exploring the efficacy of AMACR, ERG, and AR immunostains in prostatic adenocarcinoma and their association with novel grade groups
European Journal of Histochemistry·2025Open Access
Synthesis, characterization, and toxicity evaluation of ciprofloxacin–chloranilic acid charge transfer complexes: potential for anticancer applications
RSC Medicinal Chemistry·2025· 3 citedOpen Access
SBL-JP-0004: A promising dual inhibitor of JAK2 and PI3KCD against gastric cancer
Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics·2024· 2 citedOpen Access
Deciphering Immune Complexity: Single-Cell Insights into Autoimmune Myocarditis Progression
2024Open Access
Unraveling Extremely Damaging IRAK4 Variants and Their Potential Implications for IRAK4 Inhibitor Efficacy
Journal of Personalized Medicine·2023· 3 citedOpen Access
A Comprehensive Pan-Cancer Analysis Identifies CEP55 as a Potential Oncogene and Novel Therapeutic Target
Diagnostics·2023· 5 citedOpen Access
HBD-2 variants and SARS-CoV-2: New insights into inter-individual susceptibility
Frontiers in Immunology·2022· 8 citedOpen Access
Evaluation of the effect of COVID-19 mandated shift to virtual teaching on medical students' performance at King Khalid University, Abha
Journal of Taibah University Medical Sciences·2022· 6 citedOpen Access
In silico high throughput screening and in vitro validation of a novel Raf/Mek dual inhibitor against colorectal carcinoma
Biologia·2022· 1 cited
Clinicopathological features and prevalence of prostate cancer in Aseer, Saudi Arabia
Saudi Medical Journal·2022· 3 citedOpen Access
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Frequent Co-authors

Muhammad Alaa Eldeen(8), Eman Fayad(7), Hesham M. Hassan(7), Mishari Alshyarba(6), Dalal Sulaiman Alshaya(6), Prasanna Rajagopalan(5), Refaat A. Eid(5), Mohamed A. Soltan(5), Ghadi Alsharif(5), Waleed K. Abdulsahib(5), Majed Al Fayi(4), Ayed A. Dera(4), Khaled M. Darwish(4), Mohamed Samir Ahmed Zaki(3), Sameh S. Elhady(3), Farag Mamdouh(3), Aiysha Althobaiti(3), Osama Mohammed Saed Abdul‐Wahab(2), Majed Saad Shaya Al Fayi(2), Abdullah Hassan Al Murea(2)