Shuzo Sugita

University Health Network — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

41h-index6.5kcitations110works5.32yr avg
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Research Topics

Cellular transport and secretion(55), Lipid Membrane Structure and Behavior(25), Retinal Development and Disorders(24), Neuroscience and Neuropharmacology Research(20), Ion channel regulation and function(16)

Publications110 total

The exocytosis regulator complexin controls spontaneous synaptic vesicle release in a CAPS-dependent manner at C. elegans excitatory synapses
PLoS Biology·2025· 3 citedOpen Access
Segregated localization of target-SNARE proteins within presynaptic terminals of Munc18-1 deficient photoreceptors
2024· 1 citedOpen Access
Graft survival of major histocompatibility complex deficient stem cell-derived retinal cells
Communications Medicine·2024· 10 citedOpen Access
Graft cell expansion from hiPSC-RPE strip after transplantation in primate eyes with or without RPE damage
Scientific Reports·2024· 8 citedOpen Access
Investigation of the effectiveness of gelatin hydrolysate in human iPS-RPE cell suspension transplantation
Regenerative Therapy·2024· 4 citedOpen Access
SNAP-25, but not SNAP-23, is essential for photoreceptor development, survival, and function in mice
Communications Biology·2024· 6 citedOpen Access
Progenitor division and cell autonomous neurosecretion are required for rod photoreceptor sublaminar positioning
Proceedings of the National Academy of Sciences·2023· 3 citedOpen Access
SNAP-25, but not SNAP-23, is essential for photoreceptor function and survival in mice
2023Open Access
Mouse model of multiple sclerosis induced by disrupting vesicular transport in oligodendrocytes
2023Open Access
Differential Regulation of Excitatory vs Inhibitory Synaptic Release by Complexin/CPX-1 and CAPS/UNC-31 at the <i>C. elegans</i> Neuromuscular Junctions
2023Open Access
Double mutation of open syntaxin and UNC-18 P334A leads to excitatory-inhibitory imbalance and impairs multiple aspects of <i>C. elegans</i> behavior
2023Open Access
Structural and functional understanding of disease-associated mutations in V-ATPase subunit a1 and other isoforms
Frontiers in Molecular Neuroscience·2023· 12 citedOpen Access
Neuronal SNAP-23 is critical for synaptic plasticity and spatial memory independently of NMDA receptor regulation
iScience·2023· 7 citedOpen Access
Exocytic machineries differentially control mediator release from allergen-triggered RBL-2H3 cells
Inflammation Research·2023· 7 cited
The Role of Tomosyn in the Regulation of Neurotransmitter Release
Advances in neurobiology·2023
Neuronal SNAP-23 scales hippocampal synaptic plasticity and memory
2022Open Access
Neuronal SNAP-23 Is Critical for Synaptic Plasticity and Spatial Memory Independently of NMDA Receptor Regulation
SSRN Electronic Journal·2022Open Access
A ROCK inhibitor promotes graft survival during transplantation of iPS cell-derived retinal cells
Zenodo (CERN European Organization for Nuclear Research)·2021Open Access
Cholesterol synthesis inhibition promotes axonal regeneration in the injured central nervous system
Neurobiology of Disease·2021· 30 citedOpen Access
Open syntaxin overcomes exocytosis defects of diverse mutants in C. elegans
Nature Communications·2020· 22 citedOpen Access
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Frequent Co-authors

Thomas C. Südhof(15), Liping Han(7), Gayoung A. Han(6), Douglas A. Baxter(5), John H. Byrne(5), Li Wang(5), Herbert Y. Gaisano(5), Nancy T. Malintan(5), Brett M. Collins(5), Frédéric A. Meunier(5), Na‐Ryum Bin(5), Masayo Takahashi(4), Li Xie(4), Philippe P. Monnier(4), Michiko Mandai(3), Mikhail Khvotchev(3), Josep Rizo(3), Lakshmanan Arunachalam(3), Yoshihito Fujita(3), Seungmee Park(3)