Georges Orfanoudakis

Centre National de la Recherche Scientifique — France

Medicine · Health Sciences

17h-index744citations34works23.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(11), Cervical Cancer and HPV Research(8), Hepatitis B Virus Studies(5), Cancer-related Molecular Pathways(5), Bacteriophages and microbial interactions(5)

Publications34 total

Molecular mechanism of IKK catalytic dimer docking to NF-κB substrates
Nature Communications·2024· 23 citedOpen Access
Sites of disruption within E1 and E2 genes of HPV16 and association with cervical dysplasia
Journal of Medical Virology·2015· 53 cited
Prevalence of HPV16 E1‐1374^63nt variants in Greek women
Journal of Medical Virology·2014· 3 cited
Molecular and evolutionary analysis of HPV16 E6 and E7 genes in Greek women
Journal of Medical Microbiology·2013· 18 cited
Proteasomal Degradation of p53 by Human Papillomavirus E6 Oncoprotein Relies on the Structural Integrity of p53 Core Domain
PLoS ONE·2011· 52 citedOpen Access
High levels of HCV core+1 antibodies in HCV patients with hepatocellular carcinoma
Journal of General Virology·2011· 30 cited
Internal translation initiation stimulates expression of the ARF/core+1 open reading frame of HCV genotype 1b
Virus Research·2010· 14 cited
Surface plasmon resonance analysis of the binding of high‐risk mucosal HPV E6 oncoproteins to the PDZ1 domain of the tight junction protein MAGI‐1
Journal of Molecular Recognition·2010· 37 cited
Prevalence of intrinsic disorder in the hepatitis C virus ARFP/Core+1/S protein
FEBS Journal·2010· 15 cited
A single-codon mutation converts HPV16 E6 oncoprotein into a potential tumor suppressor, which induces p53-dependent senescence of HPV-positive HeLa cervical cancer cells
Oncogene·2008· 33 cited
Modification of adenovirus type 5 tropism for a preferential transduction of human papillomavirus-positive cancer cells
Archives of Virology·2008· 1 cited
A novel adenovirus vector for easy cloning in the E3 region downstream of the CMV promoter
Virology Journal·2008· 3 citedOpen Access
Defining the minimal interacting regions of the tight junction protein MAGI-1 and HPV16 E6 oncoprotein for solution structure studies
Protein Expression and Purification·2008· 19 cited
Intracellular scFvs against the viral E6 oncoprotein provoke apoptosis in human papillomavirus-positive cancer cells
Biochemical and Biophysical Research Communications·2007· 26 citedOpen Access
Structural and Functional Analysis of E6 Oncoprotein: Insights in the Molecular Pathways of Human Papillomavirus-Mediated Pathogenesis
Molecular Cell·2006· 176 citedOpen Access
P.164 Expression of the ARFP/F/core+1 protein from HCV-1b clinical isolates
Journal of Clinical Virology·2006
Binding of human papillomavirus 16 E6 to p53 and E6AP is impaired by monoclonal antibodies directed against the second zinc-binding domain of E6
Journal of General Virology·2005· 31 cited
Identification using phage display of peptides promoting targeting and internalization into HPV-transformed cell lines.
HAL (Le Centre pour la Communication Scientifique Directe)·2005· 1 cited
Binding of human papillomavirus 16 E6 to p53 and E6AP is impaired by monoclonal antibodies directed against the second zinc-binding domain of E6
HAL (Le Centre pour la Communication Scientifique Directe)·2005
Identification using phage display of peptides promoting targeting and internalization into HPV-transformed cell lines
Journal of Molecular Recognition·2004· 23 cited
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Frequent Co-authors

Étienne Weiss(9), François Deryckère(7), Gilles Travé(7), Sébastian Charbonnier(6), Murielle Masson(5), Yves Nominé(4), Bruno Kieffer(4), Magali Lagrange(4), Niki Vassilaki(4), Anissa Boumlic(4), Penelope Mavromara(4), N. Befort(4), Jean‐Pierre Ebel(4), Katia Zanier(3), D. Tsakogiannis(3), Zaharoula Kyriakopoulou(3), I. G. A. Ruether(3), Tilemachos G. Dimitriou(3), Panayotis Markoulatos(3), Charlotte Boulade-Ladame(3)