Tiffany N. Seagroves

Tulane University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index4.7kcitations176works0.32yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(47), Cancer-related Molecular Pathways(40), Cancer Treatment and Pharmacology(32), Cytokine Signaling Pathways and Interactions(22), Cancer Cells and Metastasis(21)

Publications176 total

Discovery of Potent and Brain-Penetrable Tubulin Inhibitors that Effectively Suppress Breast Cancer Brain Metastasis
Molecular Cancer Therapeutics·2025Open Access
Mineralocorticoid and glucocorticoid receptor interaction drives TGFβ1-induced triple-negative breast cancer progression to metastasis
2025Open Access
Discovery of a Potent and CNS-penetrable Anti-mitotic Agent That Shows Efficacy against Tumor Growth and Metastasis (Abstract ID: 189061)
Journal of Pharmacology and Experimental Therapeutics·2025
Abstract A019: Discovery of a potent and brain-penetrable tubulin inhibitor SB-216 that shows efficacy in primary tumor growth and brain metastasis
Molecular Cancer Therapeutics·2024
Biological activity of a stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor, 60c, in metastatic, triple-negative breast cancer
Cancer Letters·2024· 1 citedOpen Access
Biological activity of a stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor, 60c, in metastatic, triple-negative breast cancer
2024Open Access
Abstract PO3-06-13: A novel stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor targeting microtubules (60c) is effective against taxane-resistant, metastatic breast cancer
Cancer Research·2024· 1 cited
Glucocorticoid Receptors Drive Breast Cancer Cell Migration and Metabolic Reprogramming via PDK4
Endocrinology·2023· 31 citedOpen Access
Abstract 1670: Sabizabulin shows anti-cancer efficacy in HER2+ breast cancer and novel sabizabulin derivatives overcome paclitaxel-resistance in triple negative breast cancer
Cancer Research·2023
Abstract 72: Ablation of WNT10B alters the tumor microenvironment in highly metastatic breast cancer, altering paclitaxel response
Cancer Research·2023
Supplementary figure legends from Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF–driven Signaling Axis
2023Open Access
Figure S6 from An Orally Available Tubulin Inhibitor, VERU-111, Suppresses Triple-Negative Breast Cancer Tumor Growth and Metastasis and Bypasses Taxane Resistance
2023Open Access
Table S2 from An Orally Available Tubulin Inhibitor, VERU-111, Suppresses Triple-Negative Breast Cancer Tumor Growth and Metastasis and Bypasses Taxane Resistance
2023Open Access
Supplementary Tables 1 - 6 from Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer
2023Open Access
Supplemental Methods including references, Supplemental Table 1, and Supplemental Figures 1-5 from Breast Tumor Kinase (Brk/PTK6) Mediates Advanced Cancer Phenotypes via SH2-Domain Dependent Activation of RhoA and Aryl Hydrocarbon Receptor (AhR) Signaling
2023Open Access
Data from Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer
2023Open Access
Supplementary Figure 2 from Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF–driven Signaling Axis
2023Open Access
Data from Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer
2023Open Access
Supplementary Figure 4 from Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF–driven Signaling Axis
2023Open Access
Data from Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF–driven Signaling Axis
2023Open Access
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Frequent Co-authors

Raisa I. Krutilina(17), Luciana P. Schwab(11), Deanna N. Parke(10), Randall S. Johnson(7), Susan A. Krum(7), Gustavo A. Miranda‐Carboni(7), Meiyun Fan(6), Duane D. Miller(6), Wěi Li(6), Danielle L. Peacock(5), Danielle L. Brooks(5), Iram Fatima(5), Carol A. Lange(5), Hilaire C. Playa(5), Aarti Sethuraman(4), Mauricio A. Lillo(4), Hao Chen(4), Mauricio J. Reginato(3), Debbie Liao(3), Jeffrey M. Rosen(3)