Lynn L. Silver

LNK (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

40h-index13.9kcitations105works6.72yr avg
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Research Topics

Antibiotic Resistance in Bacteria(30), Bacterial Genetics and Biotechnology(18), Microbial Natural Products and Biosynthesis(18), Bacteriophages and microbial interactions(15), Antibiotic Use and Resistance(13)

Publications105 total

Lasso-shaped molecule is a new type of broad-spectrum antibiotic
Nature·2025· 2 cited
Polypharmacology
2024· 1 cited
Multi-year analysis of the global preclinical antibacterial pipeline: trends and gaps
Antimicrobial Agents and Chemotherapy·2024· 17 citedOpen Access
Reply to Kaye and Belley, “Third-Generation Cephalosporin-Resistant <i>Enterobacterales</i> Are Critical Priority Pathogens, Too!”
Antimicrobial Agents and Chemotherapy·2022· 2 citedOpen Access
Recent advances and challenges in antibacterial drug development; The editorial
ADMET & DMPK·2022· 6 citedOpen Access
Analysis of the clinical pipeline of treatments for drug resistant bacterial infections: despite progress, more action is needed.
Oxford University Research Archive (ORA) (University of Oxford)·2022· 221 citedOpen Access
Faculty Opinions recommendation of Combining cell envelope stress reporter assays in a screening approach to identify BAM complex inhibitors.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2021
Small Molecular Weapons against Multi-Drug Resistance
Accounts of Chemical Research·2021· 10 cited
Setting Our Sights on Infectious Diseases
ACS Infectious Diseases·2019· 22 citedOpen Access
The small-molecule antibiotics pipeline: 2014–2018
Nature Reviews Drug Discovery·2019· 61 cited
Perspective on Antibacterial Lead Identification Challenges and the Role of Hypothesis-Driven Strategies
SLAS DISCOVERY·2019· 12 citedOpen Access
Analysis of the clinical antibacterial and antituberculosis pipeline
The Lancet Infectious Diseases·2018· 214 cited
Faculty Opinions recommendation of Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018Open Access
Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis
The Lancet Infectious Diseases·2017· 5.8k cited
What is an “ideal” antibiotic? Discovery challenges and path forward
Biochemical Pharmacology·2017· 192 cited
Fosfomycin: Mechanism and Resistance
Cold Spring Harbor Perspectives in Medicine·2017· 305 citedOpen Access
The Antibiotic Future
Topics in medicinal chemistry·2017· 12 cited
Appropriate Targets for Antibacterial Drugs
Cold Spring Harbor Perspectives in Medicine·2016· 76 citedOpen Access
A Gestalt approach to Gram-negative entry
Bioorganic & Medicinal Chemistry·2016· 175 cited
Antibiotics and antibiotic resistance.
2016· 5 cited
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Frequent Co-authors

Katherine Young(10), Ronald E. Painter(5), Joyce Kohler(5), Srinivas Kodali(4), Sheo B. Singh(4), Nancy G. Nossal(4), Michaël Chandler(4), L. Caro(4), Ursula Theuretzbacher(3), Guy Thwaites(3), Andrew Galgoci(3), Karen Dorso(3), Kithsiri Herath(3), Fernando Peláez(3), Dennis M. Schmatz(3), Doris Cully(3), Gail G. Hammond(3), Stephan Harbarth(2), Roman S. Kozlov(2), Lorenzo Moja(2)