Paul Spiers

University of Bradford — United Kingdom

Medicine · Health Sciences

23h-index2.0kcitations106works0.02yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(12), Protease and Inhibitor Mechanisms(9), Nitric Oxide and Endothelin Effects(6), Ion channel regulation and function(6), HIV/AIDS drug development and treatment(6)

Publications106 total

14 Metformin does not reverse the effect of pharmacological inhibition of protein phosphatase 2A on VE-cadherin in human microvascular endothelial cells
Abstracts·2023Open Access
Reflecting on interpersonal practice
Elsevier eBooks·2023
Introduction
Elsevier eBooks·2023
Navigating relationships and therapeutic boundaries
Elsevier eBooks·2023
Supervision
Elsevier eBooks·2023
Defining success
Elsevier eBooks·2023
Working with challenging social contexts
Elsevier eBooks·2023
Discussing international applications
Elsevier eBooks·2023
Investigation of association of genetic variant rs3918242 of matrix metalloproteinase-9 with hypertension, myocardial infarction and progression of ventricular dysfunction in Irish Caucasian patients with diabetes: a report from the STOP-HF follow-up programme
BMC Cardiovascular Disorders·2021· 15 citedOpen Access
Arterial stiffness is associated with elastin fragmentation and medial collagen content in the human aorta
European Heart Journal·2020· 3 citedOpen Access
Haplotype of receptor for advanced glycation end products is associated with arterial stiffness in essential hypertension
European Heart Journal·2020· 1 cited
New pharmacotherapy for heart failure with reduced ejection fraction
Expert Review of Cardiovascular Therapy·2020· 4 cited
P12 Role of protein phosphatase 2a inhibition in modulation of claudin- 5 and ve-cadherin in human brain microvascular endothelial cells
2020
Protective effects of intermedin/adrenomedullin-2 in a cellular model of human pulmonary arterial hypertension
Peptides·2020· 9 cited
Hypoxia modulates protein phosphatase 2A through HIF‐1α dependent and independent mechanisms in human aortic smooth muscle cells and ventricular cardiomyocytes
British Journal of Pharmacology·2019· 17 citedOpen Access
Regulation of the phosphoprotein phosphatase 2A system and its modulation during oxidative stress: A potential therapeutic target?
Pharmacology & Therapeutics·2019· 62 cited
2 PP2A: a guardian at the gates?
Oral Presentations·2018Open Access
5 HIF-1α dependent and independent regulation of PP2A in human aortic smooth muscle cells under hypoxia
Oral Presentations·2018Open Access
RELATIONSHIP BETWEEN SMOKING AND SMOKING CESSATION WITH VASCULATURE INFLAMMATION AND ARTERIAL STIFFNESS
Journal of the American College of Cardiology·2018· 1 cited
The role of PP2A in an inflammatory induced increase in Brain Microvascular Permeability
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2018Open Access
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Frequent Co-authors

Martina Hennessy(10), Bernard Silke(8), Barbara J. McDermott(8), Elizabeth J. Kelso(5), J. Feely(4), Fiona Mulcahy(4), E J Kelso(4), Dermot Kelleher(3), Michael Barry(3), David Back(3), David Bell(3), C. Norman Scholfield(3), F Mulcahy(2), Marie McNulty(2), Azra Mahmud(2), Jenny Svärd(2), Ismail Suliman Elgenaidi(2), Dean W.G. Harron(2), Kenneth McDonald(2), Chris Watson(2)