Dakota B. Poschel

Augusta University — United States

Immunology and Microbiology · Life Sciences

9h-index638citations19works1.92yr avg
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Research Topics

Immune cells in cancer(7), Cancer Immunotherapy and Biomarkers(6), Immune Cell Function and Interaction(6), Ferroptosis and cancer prognosis(4), Cancer Research and Treatments(4)

Publications19 total

Distinct and cooperative roles of host and tumor Osteopontin in colorectal cancer liver metastasis
2026Open Access
Lipid Nanoparticle-mediated Fas Gene Immunotherapy Suppresses Autoimmune Lymphoproliferative Syndrome 3173
The Journal of Immunology·2025Open Access
Lipid nanoparticle Fas gene therapy suppresses autoimmune lymphoproliferative syndrome in mice
Blood Immunology & Cellular Therapy·2025Open Access
Slc7a5 promotes T cell anti-tumor immunity through sustaining cytotoxic T lymphocyte effector function
Oncogene·2025· 3 cited
Lipid nanoparticle-delivered IFNα2 activates Cxcl9 to increase T cell tumor recruitment to suppress lung metastasis
Journal for ImmunoTherapy of Cancer·2025· 3 citedOpen Access
PD-L1 restrains PD-1+Nrp1lo Treg cells to suppress inflammation-driven colorectal tumorigenesis
Cell Reports·2024· 6 citedOpen Access
In vitro antibody-mediated SARS-CoV-2 infection suppression through human ACE2 receptor blockade
Immunology Letters·2024· 1 citedOpen Access
PD-L1 Restrains the PD-1 <sup>hi</sup> Nrp1 <sup>lo</sup> TGFβ <sup>+</sup> Treg to block IL6 <sup>+</sup> Neutrophil tumor infiltration to Suppress Inflammation-driven Colorectal Cancer
2023Open Access
Abstract LB036: IRF8 regulates tumor cell sensitivity to intrinsic ferroptosis by repressing p53
Cancer Research·2023
Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment
Cancer Cell·2023· 113 citedOpen Access
IRF8 Regulates Intrinsic Ferroptosis through Repressing p53 Expression to Maintain Tumor Cell Sensitivity to Cytotoxic T Lymphocytes
Cells·2023· 11 citedOpen Access
IRF8: Mechanism of Action and Health Implications
Cells·2022· 45 citedOpen Access
Lipid Nanoparticle Delivery of Fas Plasmid Restores Fas Expression to Suppress Melanoma Growth <i>In Vivo</i>
ACS Nano·2022· 34 citedOpen Access
Restoring FAS Expression via Lipid-Encapsulated FAS DNA Nanoparticle Delivery Is Sufficient to Suppress Colon Tumor Growth In Vivo
Cancers·2022· 14 citedOpen Access
WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape
Journal for ImmunoTherapy of Cancer·2021· 106 citedOpen Access
Tumor PD-L1 selectively suppresses type I interferon in myeloid cells to suppress CTL recruitment to promote lung metastasis
2021Open Access
Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression
Cancers·2021· 49 citedOpen Access
Asah2 Represses the p53–Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis
The Journal of Immunology·2021· 110 citedOpen Access
Osteopontin: A Key Regulator of Tumor Progression and Immunomodulation
Cancers·2020· 143 citedOpen Access

Frequent Co-authors

Kebin Liu(18), John D. Klement(14), Dafeng Yang(13), Alyssa D. Merting(12), Priscilla S. Redd(10), Chunwan Lu(9), Huidong Shi(9), Natasha M. Savage(5), Zainab Tiamiyu(4), Padraic G. Fallon(3), Huabin Zhu(3), Yang Zhao(3), Hannah R. Moorman(2), Gang Zhou(2), David H. Munn(2), Aaron H. Colby(2), Mark W. Grinstaff(2), Jennifer L. Waller(2), Mercy Kehinde‐Ige(2), Wei Xiao(2)