Darren N. Saunders

The University of Sydney — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

38h-index5.3kcitations125works3.02yr avg
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Research Topics

Protease and Inhibitor Mechanisms(20), Ubiquitin and proteasome pathways(17), Cancer, Lipids, and Metabolism(12), Amyotrophic Lateral Sclerosis Research(9), Cancer, Hypoxia, and Metabolism(8)

Publications125 total

Development of a targeted BioPROTAC degrader selective for misfolded SOD1
Nature Communications·2025· 2 citedOpen Access
Development of a targeted BioPROTAC degrader selective for misfolded SOD1
2025· 2 citedOpen Access
Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage
Journal of Lipid Research·2024· 1 citedOpen Access
High-content analysis of proteostasis capacity in cellular models of amyotrophic lateral sclerosis (ALS)
Scientific Reports·2024· 2 citedOpen Access
Hepatic lipid droplet-associated proteome changes distinguish dietary-induced fatty liver from glucose tolerance in male mice
American Journal of Physiology-Endocrinology and Metabolism·2024· 8 citedOpen Access
ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis
Human Molecular Genetics·2023· 5 citedOpen Access
Data from Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer
2023Open Access
Data from Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer
2023Open Access
Supplementary Figures 1-3 from Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer
2023Open Access
Supplementary Figures 1-3 from Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer
2023Open Access
Supplementary Materials, Table 1-2, Figures 1-5 from Synthetic Lethality Screens Reveal RPS6 and MST1R as Modifiers of Insulin-like Growth Factor-1 Receptor Inhibitor Activity in Childhood Sarcomas
2023Open Access
Supplementary Figures from Involvement of Lyn and the Atypical Kinase SgK269/PEAK1 in a Basal Breast Cancer Signaling Pathway
2023Open Access
Data from Synthetic Lethality Screens Reveal RPS6 and MST1R as Modifiers of Insulin-like Growth Factor-1 Receptor Inhibitor Activity in Childhood Sarcomas
2023Open Access
Data from Involvement of Lyn and the Atypical Kinase SgK269/PEAK1 in a Basal Breast Cancer Signaling Pathway
2023Open Access
Data from Synthetic Lethality Screens Reveal RPS6 and MST1R as Modifiers of Insulin-like Growth Factor-1 Receptor Inhibitor Activity in Childhood Sarcomas
2023Open Access
Data from Involvement of Lyn and the Atypical Kinase SgK269/PEAK1 in a Basal Breast Cancer Signaling Pathway
2023Open Access
Supplementary Figures from Involvement of Lyn and the Atypical Kinase SgK269/PEAK1 in a Basal Breast Cancer Signaling Pathway
2023Open Access
Supplementary Materials, Table 1-2, Figures 1-5 from Synthetic Lethality Screens Reveal RPS6 and MST1R as Modifiers of Insulin-like Growth Factor-1 Receptor Inhibitor Activity in Childhood Sarcomas
2023Open Access
Hepatic Lipid Droplet-Associated Proteome Changes Distinguish Dietary-Induced Fatty Liver from Insulin Resistance in Male Mice
2023Open Access
Influence of COVID-19 restrictions on student satisfaction with undergraduate pathology teaching in an Australian University
Frontiers in Education·2022· 4 citedOpen Access
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Frequent Co-authors

Robert F. Shearer(14), Justin J. Yerbury(9), Marie Ranson(7), David R. Croucher(7), Andrew J. Hoy(6), Robert L. Sutherland(6), Seher Balaban(5), Kara L. Vine(5), Natalie E. Farrawell(5), Michelle J. Henderson(5), Jessie McKenna(5), Mary Iconomou(4), Isabella A. Lambert-Smith(4), Colin K. W. Watts(4), Amanda J. Russell(4), Samuel Aparício(3), Lisa S. Lee(3), Danny M. Hatters(3), Mark R. Wilson(3), Mark J. Cowley(3)