Trevor J. Greenhough

Keele University — United Kingdom

Materials Science · Physical Sciences

28h-index4.9kcitations138works0.02yr avg
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Research Topics

Enzyme Structure and Function(24), Protein Structure and Dynamics(16), Neonatal Respiratory Health Research(16), Boron Compounds in Chemistry(13), Glycosylation and Glycoproteins Research(10)

Publications138 total

Phosphorylation of inner core heptose is a major determinant of bacterial surface lipopolysaccharide recognition by the innate immune protein hSP-D
Journal of Biological Chemistry·2026Open Access
Crystal structures of human SP-D complexed with synthetic oligosaccharides suggest a role for phosphorylated inner core LPS saccharides in host-pathogen interactions
2025Open Access
Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen-associated carbohydrate motifs
Journal of Biological Chemistry·2023· 3 citedOpen Access
Characterisation of the Structural Requirements for the Immunomodulatory Surfactant Protein D (SP-D) to Bind to Maltose Based Ligands
2022
Structural studies of C-reactive protein
Acta Crystallographica Section A Foundations and Advances·2021· 1 citedOpen Access
Lipopolysaccharide recognition by human surfactant protein D
Acta Crystallographica Section A Foundations and Advances·2021Open Access
Bacterial lipopolysaccharide recognition by surfactant protein D
Acta Crystallographica Section A Foundations and Advances·2021Open Access
X-ray diffraction data for structure associated with PDB ID: 6ZQR
Keele University·2020Open Access
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with N-acetyl-galactosamine-4-sulfate ligand bound
2020
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with GlcNAc ligand bound
2020
Monomeric C-Reactive Protein in Serum With Markedly Elevated CRP Levels Shares Common Calcium-Dependent Ligand Binding Properties With an in vitro Dissociated Form of C-Reactive Protein
Frontiers in Immunology·2020· 27 citedOpen Access
Atomic-resolution crystal structures of the immune protein conglutinin from cow reveal specific interactions of its binding site with N-acetylglucosamine
Journal of Biological Chemistry·2019· 6 citedOpen Access
X-Ray diffraction data relating to protein structure PDB ID: 6RYG
Keele University·2019Open Access
native structure of conglutinin carbohydrate recognition domain
2019
Structure of conglutinin carbohydrate recognition domain with GlcNAc-alpha-1-phosphate bound
2019
Structure of carbohydrate recognition domain with GlcNAc bound
2019
Structural definition of hSP-D recognition of Salmonella enterica LPS inner core oligosaccharides reveals alternative binding modes for the same LPS
PLoS ONE·2018· 19 citedOpen Access
Crystal structure of human lung surfactant protein D trimeric fragment with bound ligand Salmonella enterica Minnesota R7 oligosaccharide
2017
Crystal Structure of a Complex of Surfactant Protein D (SP-D) and Haemophilus influenzae Lipopolysaccharide Reveals Shielding of Core Structures in SP-D-Resistant Strains
Infection and Immunity·2016· 15 citedOpen Access
Crystal Structure of the Tetrameric Fibrinogen-like Recognition Domain of Fibrinogen C Domain Containing 1 (FIBCD1) Protein
Journal of Biological Chemistry·2013· 31 citedOpen Access
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Frequent Co-authors

A.K. Shrive(20), Howard M. Colquhoun(9), M. G. H. Wallbridge(9), John E. Volanakis(8), John R. Helliwell(8), S.A. Rule(6), I. Burns(6), Uday Kishore(5), Dean A. A. Myles(5), Y.S. Babu(4), Patrick Waters(4), Kenneth B. M. Reid(4), John W. Campbell(4), I.J. Clifton(4), Alok Agrawal(4), János Hajdu(4), James Trotter(4), Charles E. Bugg(3), David W. Holden(3), Peter Legzdins(3)