Kadamba Papavinasasundaram

University of Massachusetts Chan Medical School — United States

Medicine · Health Sciences

28h-index3.1kcitations64works3.52yr avg
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Research Topics

Tuberculosis Research and Epidemiology(49), Mycobacterium research and diagnosis(32), Bacterial Genetics and Biotechnology(15), RNA and protein synthesis mechanisms(10), Cancer therapeutics and mechanisms(10)

Publications64 total

VadK, a Non-Canonical Kinase that Regulates the Methylcitrate Cycle and is Essential for <i>Mycobacterium tuberculosis</i> Virulence
2025Open Access
Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection
Proceedings of the National Academy of Sciences·2025· 2 citedOpen Access
Targeted delivery of antitubercular drugs using glucan lipid particles
Microbiology Spectrum·2025· 4 citedOpen Access
Frequently arising ESX-1-associated phase variants influence <i>Mycobacterium tuberculosis</i> fitness in the presence of host and antibiotic pressures
mBio·2025· 7 citedOpen Access
Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection
2024· 3 citedOpen Access
The structure of <i>Mycobacterium thermoresistibile</i> MmpS5 reveals a conserved disulfide bond across mycobacteria
Metallomics·2024· 5 citedOpen Access
Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake
PLoS Pathogens·2023· 9 citedOpen Access
High Bacillary Burden and the ESX-1 Type VII Secretion System Promote MHC Class I Presentation by <i>Mycobacterium tuberculosis</i>–Infected Macrophages to CD8 T Cells
The Journal of Immunology·2023· 18 citedOpen Access
High bacillary burden and the ESX-1 type VII secretion system promote MHC class I presentation by <i>Mycobacterium tuberculosis</i> infected macrophages to CD8 T-cells
2022Open Access
Two‐way regulation of protein expression for identification and validation of on‐target inhibitors of <i>Mycobacterium tuberculosis</i>
The FASEB Journal·2022
Chemical–genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy
Proceedings of the National Academy of Sciences·2022· 38 citedOpen Access
Author response: Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice
2022· 2 citedOpen Access
Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase
PLoS Pathogens·2021· 29 citedOpen Access
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy
2021· 2 citedOpen Access
Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in <i>Mycobacterium tuberculosis</i>
ACS Infectious Diseases·2020· 27 citedOpen Access
Host-pathogen genetic interactions underlie tuberculosis susceptibility
2020· 6 citedOpen Access
Phosphorylation on PstP Regulates Cell Wall Metabolism and Antibiotic Tolerance in Mycobacterium smegmatis
Journal of Bacteriology·2020· 15 citedOpen Access
A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response
PLoS Pathogens·2020· 32 citedOpen Access
Host immunity increases <i>Mycobacterium tuberculosis</i> reliance on cytochrome <i>bd</i> oxidase
2020Open Access
Phosphorylation on PstP regulates cell wall metabolism and antibiotic tolerance in <i>Mycobacterium smegmatis</i>
2019Open Access
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Frequent Co-authors

Christopher M. Sassetti(27), Kenan C. Murphy(10), M. Joseph Colston(10), Christina E. Baer(6), Thomas R. Ioerger(6), Elaine O. Davis(6), Eric J. Rubin(5), Megan K. Proulx(5), Sabine Ehrt(5), Dirk Schnappinger(5), Burkhard Springer(5), Yossef Av‐Gay(4), Peter Sander(4), Erik C. Böttger(4), Peter O. Oluoch(4), Charlotte J. Reames(4), Kristine M. Guinn(3), Nadine Ruecker(3), Carolina Trujillo(3), Michael G. FitzGerald(3)