Álvaro Lladser

San Sebastián University — Chile

Immunology and Microbiology · Life Sciences

27h-index2.7kcitations86works1.92yr avg
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Research Topics

Immunotherapy and Immune Responses(46), Immune Cell Function and Interaction(26), Cancer Immunotherapy and Biomarkers(15), RNA Interference and Gene Delivery(15), Cancer Cells and Metastasis(13)

Publications86 total

DNA prime and peptide boost immunization elicits robust neoantigen-specific CD8 <sup>+</sup> T cell responses and therapeutic protection in mouse tumor models
OncoImmunology·2026Open Access
Differentiation of circulating and tissue-resident memory CD8+ T cells infiltrating human renal cell carcinoma tumors 9357
The Journal of Immunology·2025Open Access
Exploring Latin America one cell at a time
Cell·2025· 1 citedOpen Access
POS0697 EGL-003: AN OPTIMIZED IL-2 MUTEIN DESIGNED TO EXPAND REGULATORY T CELLS FOR THE TREATMENT OF AUTOIMMUNE DISEASES
Annals of the Rheumatic Diseases·2025Open Access
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies
Immunity·2025· 2 citedOpen Access
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies
Immunity·2025· 16 citedOpen Access
Abstract 3767: Enhanced anti-tumor efficacy through prolonged plasma membrane retention of a novel anti-CCR8/IL2 mutein fusion antibody
Cancer Research·2025
Abstract 6080: Preferential tumor uptake and retention of EGL-001, an anti-CTLA4 -IL2 mutein fusion antibody achieving selective tumor Treg depletion
Cancer Research·2025
CD73 promotes the maturation of murine NK cells and their survival in the tumor microenvironment
Journal of Leukocyte Biology·2025· 1 cited
scExplorer: a comprehensive web server for single-cell RNA sequencing data analysis
Bioinformatics Advances·2024Open Access
scExplorer: A Comprehensive Web Server for Single-Cell RNA Sequencing Data Analysis
2024Open Access
The IP3R inhibitor desmethylxestospongin B reduces tumor cell migration, invasion and metastasis by impairing lysosome acidification and β1-integrin recycling
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2024· 4 citedOpen Access
674 Preferential tumor retention of EGL-001, a CTLA-4/CD25 antagonist fusion protein, to selectively deplete tumor Tregs and minimize peripheral toxicities: towards a first-in-human clinical study
Regular and Young Investigator Award Abstracts·2024Open Access
Unraveling the Role of JMJD1B in Genome Stability and the Malignancy of Melanomas
International Journal of Molecular Sciences·2024· 3 citedOpen Access
Long-term efficacy of adoptive cell therapy is determined by host CD8 <sup>+</sup> T cells and undermined by lymphodepleting preconditioning
2024Open Access
Long-Term Survival and Immune Response Dynamics in Melanoma Patients Undergoing TAPCells-Based Vaccination Therapy
Vaccines·2024· 5 citedOpen Access
Abstract 4079: EGL-001 is a novel immunocytokine designed to specifically target and disarm T regulatory cells in the tumor microenvironment
Cancer Research·2024· 1 cited
S-Nitrosylation in endothelial cells contributes to tumor cell adhesion and extravasation during breast cancer metastasis
Biological Research·2023· 10 citedOpen Access
Preclinical evaluation of chimeric antigen receptor T cells targeting the carcinoembryonic antigen as a potential immunotherapy for gallbladder cancer
OncoImmunology·2023· 7 citedOpen Access
Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity
Frontiers in Immunology·2023· 6 citedOpen Access
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Frequent Co-authors

Felipe Gálvez‐Cancino(13), Rodrigo Pacheco(11), Ernesto López(10), Rolf Kiessling(9), Andrew F. G. Quest(9), Flavio Salazar‐Onfray(8), Carolina Prado(7), Maarten A. Ligtenberg(6), Manuel Varas‐Godoy(6), Daniela Sauma(6), César Oyarce(6), Hugo González(5), Marı́a Rosa Bono(5), Sebastián Cruz-Gómez(5), Diego Figueroa(4), Sergio A. Quezada(4), Francisco Contreras(4), Lisette Leyton(4), Francisco Osorio‐Barrios(4), Valentina Ugalde(4)