Simon Durand

Université Claude Bernard Lyon 1 — France

Medicine · Health Sciences

8h-index1.0kcitations17works5.22yr avg
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Research Topics

Neuroblastoma Research and Treatments(7), Single-cell and spatial transcriptomics(4), Cancer Cells and Metastasis(3), Immunotherapy and Immune Responses(3), Cancer Immunotherapy and Biomarkers(2)

Publications17 total

Spatial tumour-immune ecosystems shape the efficacy of anti-PD1 immunotherapy in primary cutaneous melanoma
2025· 1 citedOpen Access
The epigenetic regulator TRIM24 controls melanoma cell dedifferentiation and resistance to treatment in melanoma
2025Open Access
ZEB1 transcription factor induces tumor cell PD-L1 expression in melanoma
Cancer Immunology Immunotherapy·2025· 4 citedOpen Access
ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions
Oncogene·2024· 17 citedOpen Access
Cancer Cell Biomechanical Properties Accompany Tspan8-Dependent Cutaneous Melanoma Invasion
Cancers·2024· 4 citedOpen Access
Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma
Nature Communications·2023· 78 citedOpen Access
ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions
2023· 4 citedOpen Access
Interplay between intrinsic reprogramming potential and microenvironment controls neuroblastoma cell plasticity and identity
2021· 15 citedOpen Access
EMT-Inducing Transcription Factors, Drivers of Melanoma Phenotype Switching, and Resistance to Treatment
Cancers·2020· 104 citedOpen Access
Abstract B78: Role of noradrenergic core regulatory circuitry transcription factors in neuroblastoma cell identity
Cancer Research·2020
Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution
Cell Reports·2020· 149 citedOpen Access
ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations
Oncotarget·2019· 9 citedOpen Access
Transcriptional programs define intratumoral heterogeneity of Ewing sarcoma at single cell resolution
2019· 8 citedOpen Access
Abstract IA02: Identity shifts in pediatric cancers
Cancer Research·2018
Abstract B20: Deciphering heterogeneity and plasticity in neuroblastoma
Cancer Research·2018
Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries
Nature Genetics·2017· 492 citedOpen Access
Identification of Small Exonic CNV from Whole-Exome Sequence Data and Application to Autism Spectrum Disorder
The American Journal of Human Genetics·2013· 162 citedOpen Access

Frequent Co-authors

Olivier Delattre(9), Isabelle Janoueix‐Lerosey(9), Valentina Boeva(8), Sylvain Baulande(8), Caroline Louis‐Brennetot(7), Cécile Pierre‐Eugène(7), Virginie Raynal(7), Julie Caramel(7), Agathe Peltier(6), Didier Surdez(6), Stéphane Dalle(6), Maxime Grimont(6), Félix Boivin(5), Laetitia Barbollat‐Boutrand(5), Anaïs Eberhardt(5), Eve Lapouble(4), Gaëlle Pierron(4), Sandrine Grossetête-Lalami(4), Gudrun Schleiermacher(4), Nadège Gruel(4)