Jeffrey D. Daubert

Cubist Pharmaceuticals (United States) — United States

Neuroscience · Life Sciences

12h-index586citations16works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Neuropeptides and Animal Physiology(13), Receptor Mechanisms and Signaling(10), Pain Mechanisms and Treatments(6), Pharmacological Receptor Mechanisms and Effects(6), Anesthesia and Pain Management(2)

Publications16 total

Use of receptor chimeras to identify small molecules with high affinity for the dynorphin A binding domain of the κ opioid receptor
Bioorganic & Medicinal Chemistry Letters·2007· 4 citedOpen Access
[3H]Alvimopan binding to the μ opioid receptor: Comparative binding kinetics of opioid antagonists
European Journal of Pharmacology·2005· 72 cited
Pharmacological Characterization of Human κ / μ Opioid Receptor Chimeras that Retain High Affinity for Dynorphin A
Current Topics in Medicinal Chemistry·2005· 12 cited
Amino acid conjugates as κ opioid receptor agonists
Bioorganic & Medicinal Chemistry Letters·2005· 2 citedOpen Access
Synthesis and evaluation of novel peripherally restricted κ-opioid receptor agonists
Bioorganic & Medicinal Chemistry Letters·2005· 22 citedOpen Access
Structure−Activity Relationships of Dynorphin A Analogues Modified in the Address Sequence
Journal of Medicinal Chemistry·2003· 27 citedOpen Access
Structure–activity relationships of dynorphin analogs substituted in positions 2 and 3
Biopolymers·2003· 9 cited
Antipruritic and antihyperalgesic actions of loperamide and analogs
Life Sciences·2002· 24 cited
Arylacetamides as peripherally restricted kappa opioid receptor agonists
Bioorganic & Medicinal Chemistry Letters·2000· 22 citedOpen Access
[Pro<sup>3</sup>]Dyn A(1−11)-NH<sub>2</sub>:  A Dynorphin Analogue with High Selectivity for the κ Opioid Receptor
Journal of Medicinal Chemistry·2000· 32 citedOpen Access
Peripheral effects of the kappa-opioid agonist EMD 61753 on pain and inflammation in rats and humans.
PubMed·1999· 93 cited
Peripheral Effects of the κ-Opioid Agonist EMD 61753 on Pain and Inflammation in Rats and Humans
Journal of Pharmacology and Experimental Therapeutics·1999· 46 cited
Loperamide (ADL 2-1294), an Opioid Antihyperalgesic Agent with Peripheral Selectivity
Journal of Pharmacology and Experimental Therapeutics·1999· 145 cited
Endomorphins fully activate a cloned human mu opioid receptor
FEBS Letters·1998· 54 citedOpen Access
Synthesis and Biological Activity of a Novel Methylamine-Bridged Enkephalin Analogue (MABE): A New Route to Cyclic Peptides and Peptidomimetics
Journal of Medicinal Chemistry·1998· 18 citedOpen Access
[3H] 1,3-di(2-tolyl) guanidine binds to a σ2 receptor on Jurkat cell membranes, but σ compounds fail to influence immunomodulatory events in human peripheral blood lymphocytes
Immunopharmacology·1996· 4 cited

Frequent Co-authors

Robert N. DeHaven(15), Joel Cassel(12), Erik Mansson(7), Diane L. DeHaven‐Hudkins(6), Virendra Kumar(5), Alan L. Maycock(4), Murray Goodman(4), Georg Schlechtingen(3), Deqi Guo(3), Luz Cortes Burgos(2), Tony L. Yaksh(2), Halina Machelska(2), M Pflüger(2), Johannes Weber(2), Mojgan Piranvisseh-Völk(2), Christoph Stein(2), Li Zhang(2), Nga N. Chung(2), Peter W. Schiller(2), Michael A. Marella(2)