Shoshana Posy

Howard Hughes Medical Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index956citations9works0.02yr avg
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Research Topics

Wnt/β-catenin signaling in development and cancer(5), Cellular Mechanics and Interactions(3), RNA Research and Splicing(3), Protein Structure and Dynamics(2), Cancer-related gene regulation(2)

Publications9 total

Molecular design principles underlying β-strand swapping in the adhesive dimerization of cadherins
Nature Structural & Molecular Biology·2011· 112 citedOpen Access
T-cadherin structures reveal a novel adhesive binding mechanism
Nature Structural & Molecular Biology·2010· 133 citedOpen Access
Linking molecular affinity and cellular specificity in cadherin-mediated adhesion
Proceedings of the National Academy of Sciences·2009· 240 citedOpen Access
Sequence and Structural Determinants of Strand Swapping in Cadherin Domains: Do All Cadherins Bind Through the Same Adhesive Interface?
Journal of Molecular Biology·2008· 60 citedOpen Access
Crystal structure of the extracellular cholinesterase-like domain from neuroligin-2
Proceedings of the National Academy of Sciences·2008· 40 citedOpen Access
Searching for Neuronal Left/Right Asymmetry: Genomewide Analysis of Nematode Receptor-Type Guanylyl Cyclases
Genetics·2006· 143 citedOpen Access
Specificity of cell–cell adhesion by classical cadherins: Critical role for low-affinity dimerization through β-strand swapping
Proceedings of the National Academy of Sciences·2005· 142 citedOpen Access
On the Role of Structural Information in Remote Homology Detection and Sequence Alignment: New Methods Using Hybrid Sequence Profiles
Journal of Molecular Biology·2003· 86 cited
Sequence and structural determinants of strand swapping and binding affinity in cadherin domains

Frequent Co-authors

Barry Honig(8), Lawrence Shapiro(6), Göran Ahlsén(3), Fabiana Bahna(3), Jérémie Vendôme(3), Xiangshu Jin(3), Phinikoula S. Katsamba(2), Thomas M. Jessell(2), Avinoam Ben‐Shaul(2), K.J. Carroll(1), Manisha Rajebhosale(1), Stephen R. Price(1), Christopher O. Ortiz(1), John F. Etchberger(1), Christian Frøkjær‐Jensen(1), Shawn R. Lockery(1), Oliver Hobert(1), Chien Peter Chen(1), Carlo Ciatto(1), Niccolò Zampieri(1)