Sigrun R. Hofmann

Klinikum im Friedrichshain — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index1.8kcitations27works1.52yr avg
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Research Topics

Inflammasome and immune disorders(13), Osteomyelitis and Bone Disorders Research(9), Immune Response and Inflammation(7), Spondyloarthritis Studies and Treatments(4), Neonatal Respiratory Health Research(2)

Publications27 total

Genetische Variante im SCN4A-Gen als mögliche Ursache einer schweren kongenitalen Myopathie
Zeitschrift für Geburtshilfe und Neonatologie·2025
Tissue gene expression profiles and communication networks inform candidate blood biomarker identification in psoriasis and atopic dermatitis
Clinical Immunology·2024· 3 citedOpen Access
Gathering expert consensus to inform a proposed trial in chronic nonbacterial osteomyelitis (CNO)
Clinical Immunology·2023· 22 citedOpen Access
De novoCIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin-associated autoinflammatory diseases
UNC Libraries·2020· 73 citedOpen Access
Fall 5 – Die postoperative Verlegung
2019
Chronic Nonbacterial Osteomyelitis: Pathophysiological Concepts and Current Treatment Strategies
The Journal of Rheumatology·2016· 129 cited
Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO)
Rheumatology International·2016· 86 cited
Altered expression of IL-10 family cytokines in CRMO result in enhanced inflammasome activation
Pediatric Rheumatology·2015· 2 citedOpen Access
Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1β expression and release
Clinical Immunology·2015· 116 cited
Current Knowledge on Procaspase-1 Variants with Reduced or Abrogated Enzymatic Activity in Autoinflammatory Disease
Current Rheumatology Reports·2015· 11 cited
Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO)
Pediatric Rheumatology·2013· 207 citedOpen Access
PW03-025 - Procaspase-1 contributes to inflammation via NF-KB
Pediatric Rheumatology·2013Open Access
Recent Advances in Autoinflammatory Diseases and Animal Models
Journal of Genetic Syndromes & Gene Therapy·2013· 3 cited
Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression
Clinical Immunology·2012· 111 cited
Stabilisation of Cardiopulmonary Function in Newborns with Congenital Diaphragmatic Hernia Using Lung Function Parameters and Hemodynamic Management
Klinische Pädiatrie·2012· 12 cited
Agenesis of the ductus venosus—A case with favorable outcome after early signs of cardiac failure
Journal of Clinical Ultrasound·2012· 8 cited
Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury
Clinical Immunology·2012· 164 cited
Contents Vol. 32, 2012
Fetal Diagnosis and Therapy·2012
Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO)
International Journal of Rheumatology·2012· 70 citedOpen Access
De novo <i>CIAS1</i> mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal‐onset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin‐associated autoinflammatory diseases
Arthritis & Rheumatism·2002· 698 citedOpen Access
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Frequent Co-authors

Christian M. Hedrich(10), Angela Rösen‐Wolff(9), Henner Morbach(7), Hermann Girschick(4), Joachim Roesler(4), Anne Sophie Kubasch(3), Hermann Girschick(3), Gabriele Hahn(3), Antje Heilmann(3), G Kamin(3), Ivona Aksentijevich(2), Miroslawa Nowak(2), Mustapha Mallah(2), Jae Jin Chae(2), Wendy T. Watford(2), Ricardo Russo(2), Peter B. Dent(2), Helene F. Rosenberg(2), Elaine F. Remmers(2), James E. Balow(2)