Charles R. Midgett

Dartmouth College — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index709citations26works0.82yr avg
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Research Topics

Vibrio bacteria research studies(11), Bacterial Genetics and Biotechnology(5), Neuroscience and Neuropharmacology Research(4), Salmonella and Campylobacter epidemiology(4), Escherichia coli research studies(4)

Publications26 total

Crystal structure of the <i>V. parahaemolyticus</i> ToxS dimer suggests a model for bile-induced ToxRS activation
2026Open Access
Characterization of the ligand binding pocket of the virulence regulator Rns, a member of the AraC/XylS family of transcription factors
mSphere·2025Open Access
Characterization of the ligand binding pocket of the virulence regulator Rns, a Member of the AraC/XylS family of transcription factors
2025Open Access
<i>Vibrio cholerae</i> CsrA controls ToxR levels by increasing the stability and translation of <i>toxR</i> mRNA
mBio·2024· 4 citedOpen Access
<i>Vibrio cholerae</i> CsrA controls ToxR levels by increasing the stability and translation of <i>toxR</i> mRNA
2024Open Access
Structural Insights into Regulation of Vibrio Virulence Gene Networks
Advances in experimental medicine and biology·2023· 1 cited
An Enantiodefined Conformationally Constrained Fatty Acid Mimetic and Potent Inhibitor of ToxT
ACS Medicinal Chemistry Letters·2021· 8 citedOpen Access
Structure of the master regulator Rns reveals an inhibitor of enterotoxigenic Escherichia coli virulence regulons
Scientific Reports·2021· 20 citedOpen Access
Structural analysis of the master regulator Rns reveals a small molecule inhibitor of enterotoxigenic <i>Escherichia coli</i> virulence
2020Open Access
Publisher Correction: A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts
Scientific Reports·2020· 2 citedOpen Access
A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts
Scientific Reports·2020· 14 citedOpen Access
A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts
2020· 2 citedOpen Access
The Se-Met Structure of the Vibrio vulnificus ToxR periplasmic domain
2019
Intra-chain disulfide bonded ToxR periplasmic domain from Vibrio vulnificus
2019
Bile salts and alkaline p<scp>H</scp>reciprocally modulate the interaction between the periplasmic domains of<scp><i>V</i></scp><i>ibrio cholerae</i><scp>T</scp>ox<scp>R</scp>and<scp>T</scp>ox<scp>S</scp>
Molecular Microbiology·2017· 45 citedOpen Access
Reconstitution of Homomeric GluA2flop Receptors in Supported Lipid Membranes
Journal of Biological Chemistry·2013· 7 citedOpen Access
Reconstitution of homomeric GluA2(flop) receptors in supported lipid membranes: functional and structural properties.
Oxford University Research Archive (ORA) (University of Oxford)·2013· 1 cited
Domain Architecture of a Calcium-Permeable AMPA Receptor in a Ligand-Free Conformation
Frontiers in Molecular Neuroscience·2012· 19 citedOpen Access
Prostacyclin Receptor Regulation --- from Transcription to Trafficking
Current Molecular Medicine·2011· 33 cited
A stochastic kinematic model of class averaging in single-particle electron microscopy
The International Journal of Robotics Research·2011· 35 cited
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Frequent Co-authors

F. Jon Kull(14), Dean R. Madden(6), Rachel A. Swindell(5), Maria Pellegrini(4), Kacey M. Talbot(4), George P. Munson(4), Jessica D. Tolbert(3), Corinne D. Strickland(2), Monique M. Ryan(2), Susan T. Iannaccone(2), Nigel G. Laing(2), Alan H. Beggs(2), Jeremiah Stitham(2), Kathleen A. Martin(2), John Hwa(2), Jessica L. Day(2), Jelena Baranovic(2), Chandra S. Ramanujan(2), Keiichi Torimitsu(2), Alexandra R. Mey(2)