Guy Lenaers

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

55h-index13.3kcitations314works2.72yr avg
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Research Topics

Mitochondrial Function and Pathology(151), ATP Synthase and ATPases Research(61), Metabolism and Genetic Disorders(42), Retinal Development and Disorders(32), Immune cells in cancer(18)

Publications314 total

Genetic diversity of Usher syndrome in Moroccan patients
Human Genetics·2026
Accumulation of complex I assembly intermediates in a novel presentation of RTN4IP1-related disorder with developmental delay, ataxia and dyskinesia
Molecular Genetics and Metabolism·2025
G-quadruplex ligand RHPS4 compromises cellular radioresistance by inhibiting the mitochondrial adaptive response induced by ionizing irradiation
NAR Cancer·2025· 1 citedOpen Access
Novel splice variants implicated in inherited retinal dystrophies in two Moroccan families
Molecular Biology Reports·2025
A Tunisian POLG mutation expands the clinical spectrum of POLG-related disorders
Mitochondrion·2025
Altered endothelial mitochondrial Opa1‐related fusion in mouse accelerates age‐associated vascular and kidney damage
Physiological Reports·2025Open Access
Identification of the genetic causes of inherited diseases in a North African biobank: implications for genetic diagnosis
Molecular Syndromology·2025
<i>HCN2</i>‐Associated Neurodevelopmental Disorders: Data from Patients and <i>Xenopus</i> Cell Models
Annals of Neurology·2025· 5 citedOpen Access
Bi-allelic variants in TM2D3 cause a severe syndromic neurodevelopmental disorder associated with endoplasmic reticulum and mitochondrial abnormalities
The American Journal of Human Genetics·2025Open Access
Heart of the matter: Mitochondrial dynamics and genome alterations in cardiac aging
Mechanisms of Ageing and Development·2025· 8 citedOpen Access
Altered endothelial mitochondrial Opa1-related fusion in mouse amplifies age-associated vascular and kidney damages
2025Open Access
Neurotoxins Acting on TRPV1—Building a Molecular Template for the Study of Pain and Thermal Dysfunctions
Toxins·2025· 1 citedOpen Access
Two Cases of ROSAH-Like Syndrome Restricted to the Ophthalmologic Presentation
Ocular Immunology and Inflammation·2025· 1 cited
Identification of biomarkers reflecting opa1‐related dominant optic atrophy severity to infer patient cohorts eligible to clinical trials
Acta Ophthalmologica·2025
Biallelic <i>NDUFA13</i> variants lead to a neurodevelopmental phenotype with gradual neurological impairment
Brain Communications·2024· 2 citedOpen Access
G-quadruplex ligand RHPS4 compromises cellular radio-resistance by blocking the increase in mitochondrial mass and activity induced by ionising irradiation
2024· 1 citedOpen Access
Glycogenesis and glyconeogenesis from glutamine, lactate and glycerol support human macrophage functions
EMBO Reports·2024· 11 citedOpen Access
A human mitochondrial isoform of TRPV1 regulates intracellular Ca2+ simultaneously with mitochondrial thermolysis
2024Open Access
A human mitochondrial isoform of TRPV1 regulates intracellular Ca2+ simultaneously with mitochondrial thermolysis
2024· 2 citedOpen Access
Identification of biomarkers reflecting OPA1-related Dominant Optic Atrophy severity to infer patient cohorts eligible to clinical trials
Biochimica et Biophysica Acta (BBA) - Bioenergetics·2024
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Frequent Co-authors

Pascal Reynier(25), Cécile Delettre(17), Patrizia Amati‐Bonneau(17), Dominique Bonneau(17), Vincent Procaccio(16), Pascale Belenguer(11), Aurélien Olichon(10), Christian Hamel(9), Arnaud Chevrollier(8), Naïg Guéguen(7), Laetitia Pelloquin(6), Valério Carelli(6), Dan Miléa(6), Gilles Simard(6), Christian P. Hamel(5), Emmanuelle Sarzi(5), Céline Bris(5), Majida Charif(5), Stéphanie Leruez(5), Valérie Desquiret‐Dumas(5)