Christopher G. Tate

MRC Laboratory of Molecular Biology — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

65h-index17.7kcitations205works3.22yr avg
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Research Topics

Receptor Mechanisms and Signaling(123), Neuropeptides and Animal Physiology(56), Monoclonal and Polyclonal Antibodies Research(29), Adenosine and Purinergic Signaling(20), Mass Spectrometry Techniques and Applications(19)

Publications205 total

Author response: Insights from aquaporin structures into drug-resistant sleeping sickness
2026Open Access
Purification of the Active-State G Protein-Coupled Receptor ADGRL4 for Cryo-Electron Microscopy Using a Modular Tag System and a Tethered mini-G<sub>q</sub>
BIO-PROTOCOL·2026· 1 citedOpen Access
aGPCR-HEK: A Stable High-Expression Inducible Mammalian Cell Expression System for Adhesion GPCR Structural Biology Applications
BIO-PROTOCOL·2026Open Access
Insights from aquaporin structures into drug-resistant sleeping sickness
eLife·2025Open Access
Structure of the Gq-coupled adhesion receptor ADGRL4
Nature Communications·2025· 1 citedOpen Access
Author response: Insights from aquaporin structures into drug-resistant sleeping sickness
2025Open Access
Insights from aquaporin structures into drug-resistant sleeping sickness
2025Open Access
Structure of the G <sub>q</sub> -coupled adhesion receptor ADGRL4, a GPCR implicated in cancer
2025Open Access
UDP-glucose Activation of a G-protein/Sucrose Synthase Signaling Supercomplex
2025Open Access
28P The first high-resolution structure of the Gq-coupled adhesion receptor ADGRL4, a GPCR implicated in multiple cancers
Annals of Oncology·2025
Insights from aquaporin structures into drug-resistant sleeping sickness
eLife·2025Open Access
Insights from aquaporin structures into drug-resistant sleeping sickness
2025Open Access
Insights from aquaporin structures into drug-resistant sleeping sickness
2025· 1 citedOpen Access
Structure of the Gq-coupled adhesion receptor ADGRL4.
Apollo (University of Cambridge)·2025
<i>De novo</i> design of miniprotein agonists and antagonists targeting G protein-coupled receptors
2025· 12 citedOpen Access
Functional dynamics of G protein-coupled receptors reveal new routes for drug discovery
Nature Reviews Drug Discovery·2025· 44 citedOpen Access
VPS26 Moonlights as a β‑Arrestin-like Adapter for a 7‑Transmembrane RGS Protein in Arabidopsis thaliana
UNC Libraries·2024Open Access
VPS26 Moonlights as a β-Arrestin-like Adapter for a 7-Transmembrane RGS Protein in <i>Arabidopsis thaliana</i>
Biochemistry·2024· 2 citedOpen Access
Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f
Nature Communications·2024· 10 citedOpen Access
Cryo-EM Structures of the Fungal GPCR Dimer Ste2
2024
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Frequent Co-authors

Tony Warne(13), Patricia C. Edwards(11), Andrew G. W. Leslie(10), Gebhard F. X. Schertler(7), Rony Nehmé(7), Francesca Magnani(6), Byron Carpenter(6), Javier García‐Nafría(6), Guillaume Lebon(5), María J. Serrano‐Vega(5), Reinhard Grisshammer(5), Yoko Shibata(4), AJ Venkatakrishnan(3), M. Madan Babu(3), R. Moukhametzianov(3), K.A. Bennett(3), A.S. Dore(3), Miles Congreve(3), Yang Lee(3), Xavier Deupí(2)