Sofía Sirvent

Universidad Complutense de Madrid — Spain

Medicine · Health Sciences

18h-index1.0kcitations39works6.02yr avg
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Research Topics

Allergic Rhinitis and Sensitization(18), Food Allergy and Anaphylaxis Research(16), T-cell and B-cell Immunology(13), Immunotherapy and Immune Responses(11), Contact Dermatitis and Allergies(10)

Publications38 total

IgE, anti-IgE therapy, and regulatory T cells: new paradigms in allergic inflammation
Frontiers in Allergy·2026Open Access
The Role of <scp>IgE</scp> in Crohn's Disease by Impairing the Capacity of Plasmacytoid Dendritic Cells to Generate <scp>FOXP3</scp> <sup>+</sup> Tregs
Allergy·2025· 4 citedOpen Access
Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity
Science Immunology·2024· 8 citedOpen Access
The Role of Regulatory T Cells in Allergic Diseases: Collegium Internationale Allergologicum (CIA) Update 2024
International Archives of Allergy and Immunology·2024· 12 cited
Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity
2023· 1 citedOpen Access
Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis
Nature Communications·2023· 7 citedOpen Access
Impaired expression of metallothioneins contributes to Th17/TNF- mediated, allergen-induced inflammation in patients with atopic dermatitis.
Figshare·2023Open Access
Skin programming of inflammatory responses to <i>Staphylococcus aureus</i> is compartmentalized according to epidermal keratinocyte differentiation status
British Journal of Dermatology·2022· 7 citedOpen Access
Transcriptional programming of immunoregulatory responses in human Langerhans cells
Frontiers in Immunology·2022· 4 citedOpen Access
Genetic Algorithm with Rank Selection optimises robust parameter estimation for systems biology models
2022Open Access
TNFα SIGNALLING IN THE CUTANEOUS IMMUNE NETWORK INSTRUCTS LOCAL Th17 ALLERGEN-SPECIFIC INFLAMMATORY RESPONSES IN ATOPIC DERMATITIS
2021Open Access
An IRF1-IRF4 Toggle-Switch Controls Tolerogenic and Immunogenic Transcriptional Programming in Human Langerhans Cells
Frontiers in Immunology·2021· 15 citedOpen Access
TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity
2021Open Access
Machine learning applied to atopic dermatitis transcriptome reveals distinct therapy‐dependent modification of the keratinocyte immunophenotype*
British Journal of Dermatology·2020· 22 citedOpen Access
Genomic programming of IRF4-expressing human Langerhans cells
Nature Communications·2020· 31 citedOpen Access
Langerhans cells immunocompetency is critical for IDO1-dependent ability to induce tolerogenic T cells
2019· 5 citedOpen Access
Single cell transcriptomic analysis identifies Langerhans cells immunocompetency is critical for IDO1- dependent ability to induce tolerogenic T cells.
2019· 4 cited
Machine learning applied to atopic dermatitis transcriptome reveals distinct therapy-dependent modification of the keratinocyte immunophenotype
2019Open Access
Data on genomic profiles, epigenomic profiles, phenotypic and functional characteristics of primary human Langerhans cells
Figshare·2019Open Access
Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells
2019· 2 citedOpen Access
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Frequent Co-authors

Andrés F. Vallejo(18), Marta E. Polak(18), James Davies(17), Óscar Palomares(16), Kalum Clayton(15), Michael R. Ardern‐Jones(15), Rosalı́a Rodrı́guez(13), Javier Cuesta‐Herranz(12), Mayte Villalba(12), Jonathan West(8), Ben D. MacArthur(8), Harinder Singh(8), Patrick S. Stumpf(7), Gemma Porter(7), Andrea Vereda(5), Peter S. Friedmann(5), José Luis Subiza(4), Alba Angelina(4), Nigel Hall(4), Clare L. Bennett(4)