M.A. Naughton

Eli Lilly (United States) — United States

Medicine · Health Sciences

5h-index977citations5works0.02yr avg
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Research Topics

Platelet Disorders and Treatments(4), Cell Adhesion Molecules Research(2), Blood Coagulation and Thrombosis Mechanisms(2), Coagulation, Bradykinin, Polyphosphates, and Angioedema(2), Chemical Synthesis and Analysis(1)

Publications5 total

Fibrinogen Receptor (GPIIb-IIIa) Antagonists Derived from 5,6-Bicyclic Templates. Amidinoindoles, Amidinoindazoles, and Amidinobenzofurans Containing the <i>N</i>-α-Sulfonamide Carboxylic Acid Function as Potent Platelet Aggregation Inhibitors
Journal of Medicinal Chemistry·1997· 18 citedOpen Access
Thrombin receptor antagonists derived from “tethered ligand”agonist peptides
Peptides·1994· 5 cited
Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa.
Journal of Biological Chemistry·1993· 371 citedOpen Access
Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms.
Journal of Biological Chemistry·1993· 293 citedOpen Access
Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function.
Journal of Biological Chemistry·1992· 290 citedOpen Access

Frequent Co-authors

Jack W. Rose(5), Ann Arfsten(4), Robert M. Scarborough(3), David R. Phillips(2), L Nannizzi(2), Andrew Campbell(2), Israel Charo(2), R. M. Scarborough(2), Willy Teng(2), Wei-Ning Teng(1), David T. Hung(1), T K Vu(1), V I Wheaton(1), Christoph W. Turck(1), Shaun R. Coughlin(1), Ting Su(1), Mark S. Smyth(1), Jefferson R. McCowan(1), Joseph A. Jakubowski(1), Virginia L. Wyss(1)