James Turkson

Cedars-Sinai Medical Center — United States

Medicine · Health Sciences

53h-index18.9kcitations218works0.32yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Cytokine Signaling Pathways and Interactions(111), PI3K/AKT/mTOR signaling in cancer(34), Cancer Mechanisms and Therapy(32), Synthesis and biological activity(29), Cancer, Lipids, and Metabolism(19)

Publications218 total

Targeting STAT3 Promotes Tumor Cell Death and Enhances T-Cell Activity in HPV16-Positive Cancer
Cancers·2026Open Access
Developing an antibody drug encapsulation nanoagent targeting HER2 for cancer treatment
Journal of Translational Medicine·2026Open Access
Exploring the Tumour Microenvironment (TME) in AIDS-Defining Cancers (ADC) and Non-AIDS Defining Cancers (NADC) in the HIV Population: Implications on Remission, Relapse and Resistance
Stem Cell Reviews and Reports·2025Open Access
Abstract 1741: STAT3 Orchestrates common and divergent mechanisms in different cell types to promote pancreatic cancer development and progression
Cancer Research·2025
Small Molecule Induces Time‐Dependent Inhibition of Stat3 Dimerization and DNA‐Binding Activity and Regresses Human Breast Tumor Xenografts
ChemBioChem·2024· 2 citedOpen Access
Abstract 663: Irreversible covalent azetidine-based small molecule inhibitors of Stat3 activity block growth of human pancreatic tumors
Cancer Research·2024
Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3
Bioorganic & Medicinal Chemistry Letters·2023· 3 citedOpen Access
Retraction of “Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies”
ACS Medicinal Chemistry Letters·2023Open Access
357 A NOVEL AZETIDINE-BASED STAT3 INHIBITOR INDUCES ANTI-TUMOR RESPONSES IN EXPERIMENTAL MODELS OF PANCREATIC CANCER
Gastroenterology·2023
Abstract 514: Novel potent azetidine-based inhibitors bind irreversibly to Stat3 DNA-binding domain (DBD) and are efficacious against tumor growth in mice
Cancer Research·2023
Abstract 2782: Small molecule H182 suppresses Stat3 activation in tumor cells and combines with radiation therapy to block breast tumor growth in mouse syngeneic models
Cancer Research·2023
Figure S4 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
2023Open Access
Figure S5 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
2023Open Access
Supplementary Material, Text for publication from 15α-methoxypuupehenol Induces Antitumor Effects <i>In Vitro</i> and <i>In Vivo</i> against Human Glioblastoma and Breast Cancer Models
2023Open Access
Figure S3 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
2023Open Access
Figure S3 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
2023Open Access
Figure S7 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
2023Open Access
Data from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
2023Open Access
Data from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
2023Open Access
Figure S1 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells
2023Open Access
page 1 of 11Next →

Frequent Co-authors

Richard Jove(26), Peibin Yue(10), Saı̈d M. Sebti(8), Shumin Zhang(7), Patrick T. Gunning(7), Xiaolei Zhang(6), Tammy Bowman(5), Eric B. Haura(5), Steven Fletcher(5), Khandaker Siddiquee(4), Brent D. G. Page(4), Wei Zhao(4), David Paladino(4), Valeria Poli(4), Guilian Niu(3), Mei Huang(3), James G. Karras(3), Hua Yu(3), Jin Cheng(3), Andrew D. Hamilton(3)