Brittany L. Jacobs

University of Wisconsin System — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index858citations10works0.02yr avg
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Research Topics

Muscle Physiology and Disorders(7), PI3K/AKT/mTOR signaling in cancer(5), Ion channel regulation and function(3), Cellular transport and secretion(2), Cardiomyopathy and Myosin Studies(2)

Publications10 total

The role of raptor in the mechanical load‐induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy
The FASEB Journal·2018· 146 citedOpen Access
Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling
Journal of Biological Chemistry·2017· 33 citedOpen Access
Yes‐Associated Protein is up‐regulated by mechanical overload and is sufficient to induce skeletal muscle hypertrophy
FEBS Letters·2015· 109 citedOpen Access
A role for Raptor phosphorylation in the mechanical activation of mTOR signaling
Cellular Signalling·2013· 57 citedOpen Access
The mechanical activation of mTOR signaling: an emerging role for late endosome/lysosomal targeting
Journal of Muscle Research and Cell Motility·2013· 49 citedOpen Access
Eccentric contractions increase the phosphorylation of tuberous sclerosis complex‐2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome
The Journal of Physiology·2013· 91 citedOpen Access
Muscle Fiber Type-Dependent Differences in the Regulation of Protein Synthesis
PLoS ONE·2012· 82 citedOpen Access
The role of skeletal muscle mTOR in the regulation of mechanical load‐induced growth
The Journal of Physiology·2011· 291 citedOpen Access
C2C12 cell culture model for investigating Ca <sup>2+</sup> ‐dependence of myocyte differentiation
The FASEB Journal·2011
The Role of mTOR in Mechanical Load Induced Skeletal Muscle Hypertrophy and Hyperplasia
The FASEB Journal·2011

Frequent Co-authors

Troy A. Hornberger(9), Craig A. Goodman(8), Jae‐Sung You(6), John W. Frey(4), Rachel M. McNally(3), Danielle Mabrey(2), Hannah C. Lincoln(2), Rachel E. Privett(2), David M. Gundermann(2), Kuan‐Hung Lin(1), Nate D. Steinert(1), Jason M. Dietz(1), Jack A. Kotecki(1), Kookjoo Kim(1), Rocky Blanco(1), Dapeng Chen(1), Eva R. Chin(1)