Wei Keat Lim

Regeneron (United States) — United States

Immunology and Microbiology · Life Sciences

23h-index6.6kcitations86works3.02yr avg
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Research Topics

IL-33, ST2, and ILC Pathways(20), Eosinophilic Esophagitis(14), Asthma and respiratory diseases(13), Bioinformatics and Genomic Networks(12), Gene expression and cancer classification(8)

Publications86 total

Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade
2025· 1 citedOpen Access
Author response: Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade
2025Open Access
Optimized murine sample sizes for RNA sequencing studies revealed from large scale comparative analysis
Nature Communications·2025· 2 citedOpen Access
209 IL-4 coordinates IgE-dependent effector cell responses
Journal of Investigative Dermatology·2025Open Access
The IL-33 and IL-4Rα blocking antibodies itepekimab and dupilumab modulate both distinct and common inflammatory mediators in asthma
Science Translational Medicine·2025· 4 cited
Divergent T Cell Phenotypes Define Pediatric Crohn’s Disease and Ulcerative Colitis
2025· 1 citedOpen Access
B cells and Plasma Cells accumulate in lung during allergen-driven airway inflammation and aggregate into tertiary lymphoid follicles
2025
1010 The oxazolone challenge model captures key features of human atopic dermatitis
Journal of Investigative Dermatology·2025Open Access
OP0138 IL-33 EXPANDS PLASMA CELLS, DISRUPTS GERMINAL CENTERS AND INCREASES AUTOANTIBODY PRODUCTION
Annals of the Rheumatic Diseases·2025Open Access
Transcriptional Fingerprinting of Type 2 Cytokines, IL-4, IL-13, IL-5 and the Alarmin IL-33 Reveals Unique and Shared Inflammatory Pathways in Asthma
American Journal of Respiratory and Critical Care Medicine·2025
TSLP-Induced Type 2 Airway Inflammation and Remodeling is Dependent on IL-4R⍺ Signaling in Mice
American Journal of Respiratory and Critical Care Medicine·2025
Chronic Allergen Exposure Leads to Accumulation of B Cells in Lung Lymphoid Aggregates With Genes Associated With Germinal Center Activity and Plasma Cell Differentiation
American Journal of Respiratory and Critical Care Medicine·2025
From Mice to Humans: The IL-33 and IL-4Rα Blocking Antibodies, Itepekimab and Dupilumab, Modulate Distinct and Common Inflammatory Mediators in Asthma
American Journal of Respiratory and Critical Care Medicine·2025
The <scp>IL</scp>‐4–<scp>IL</scp>‐<scp>4Rα</scp> axis modulates olfactory neuroimmune signaling to induce loss of smell
Allergy·2024· 7 citedOpen Access
Peripheral human red blood cell development in human immune system mouse model with heme oxygenase-1 deficiency
Blood Advances·2024· 1 citedOpen Access
Lymphoid aggregates accumulate in the lung during allergen-driven airway inflammation and serve as a local source of IgE production
2024
IgE plasma cells are transcriptionally and functionally distinct from other isotypes
Science Immunology·2024· 22 citedOpen Access
765 IL-4 plays a dominant role, relative to IL-13, in IgE-dependent human mast cell responses
Journal of Investigative Dermatology·2024Open Access
Digital wearable insole-based identification of knee arthropathies and gait signatures using machine learning
eLife·2024· 9 citedOpen Access
Differential Regulation of the Type 2 Cytokines, IL-4 and IL-13, and the Alarmins, IL-33 and TSLPA, in Airway Inflammation and Remodeling
2024
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Frequent Co-authors

Andrea Califano(15), Andrew Murphy(14), Matthew A. Sleeman(14), Jamie Orengo(13), George Scott(8), Dylan Birchard(8), Seblewongel Asrat(8), Matthew F. Wipperman(8), Kirsten Nagashima(7), Gurinder S. Atwal(7), Sara Hamon(7), Riccardo Dalla‐Favera(6), Jeanne Allinne(6), George D. Yancopoulos(6), Jennifer D. Hamilton(6), Katia Basso(6), Sokol Haxhinasto(6), Kaitlyn Gayvert(6), Audrey Le Floc’h(5), Kai Wang(5)