Andrej Maroz

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index765citations23works0.02yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(10), Photochemistry and Electron Transfer Studies(6), Metal complexes synthesis and properties(3), Epigenetics and DNA Methylation(3), DNA and Nucleic Acid Chemistry(3)

Publications23 total

Supplementary Methods, Tables 1-5, Figures 1-9 from Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302
2023Open Access
Supplementary Methods, Tables 1-5, Figures 1-9 from Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302
2023Open Access
Data from Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302
2023Open Access
Data from Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302
2023Open Access
The reduction potential of the slipped GC base pair in one-electron oxidized duplex DNA
Physical Chemistry Chemical Physics·2019· 3 cited
Characterisation of radicals formed by the triazine 1,4-dioxide hypoxia-activated prodrug, SN30000
Organic & Biomolecular Chemistry·2014· 27 cited
A Mitochondria-Targeted Macrocyclic Mn(II) Superoxide Dismutase Mimetic
Chemistry & Biology·2012· 56 cited
Identification of a lead hypoxia-activated irreversible pan-HER inhibitor SN32807 (PR509) by pharmacokinetic and anti-tumor efficacy screening in an erlotinib-resistant xenograft model
ResearchSPAce (Bath Spa University)·2012
Molecular and Cellular Pharmacology of the Hypoxia-Activated Prodrug TH-302
Molecular Cancer Therapeutics·2011· 203 cited
Abstract A247: Mechanism of action of the hypoxia-activated irreversible pan-HER inhibitor SN29966.
Molecular Cancer Therapeutics·2011· 4 cited
Spectral and kinetic evidence for reaction of superoxide with compound I of myeloperoxidase
Free Radical Biology and Medicine·2011· 24 cited
Abstract LB-297: Characterization of novel hypoxia-activated prodrugs of irreversible pan-HER inhibitors
Cancer Research·2010
Characterization of Radicals Formed Following Enzymatic Reduction of 3-Substituted Analogues of the Hypoxia-Selective Cytotoxin 3-Amino-1,2,4-Benzotriazine 1,4-Dioxide (Tirapazamine)
Journal of the American Chemical Society·2010· 44 cited
Abstract C46: Design and identification of the novel hypoxia-activated irreversible pan-HER inhibitor SN29966
Molecular Cancer Therapeutics·2009· 4 cited
Release of nitrite from the antitubercular nitroimidazoledrug PA-824 and analogues upon one-electron reduction in protic, non-aqueous solvent
Organic & Biomolecular Chemistry·2009· 14 cited
One-Electron Reduction Potential of the Neutral Guanyl Radical in the GC Base Pair of Duplex DNA
Journal of the American Chemical Society·2009· 41 citedOpen Access
Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity
Free Radical Biology and Medicine·2008· 133 cited
Pulse Radiolysis Investigation on the Mechanism of the Catalytic Action of Mn(II)−Pentaazamacrocycle Compounds as Superoxide Dismutase Mimetics
The Journal of Physical Chemistry A·2008· 45 cited
Intermediates in the reduction of the antituberculosis drug PA-824, (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine, in aqueous solution
Organic & Biomolecular Chemistry·2008· 33 cited
Cytosine-Gated Hole Creation and Transfer in DNA in Aqueous Solution
Journal of the American Chemical Society·2006· 36 cited
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Frequent Co-authors

Robert F. Anderson(14), Adam V. Patterson(11), William A. Denny(8), S.S. Shinde(7), Christopher P. Guise(6), Deepthi Bhupathi(5), Monica Banica(5), Lingyun Lan(5), Gustavo Lorente(5), Jianxin Duan(5), Alexandra M. Mowday(5), Gregory C. Stachelek(5), Peter M. Glazer(5), Mark D. Matteucci(5), Charles P. Hart(5), Robert F. Anderson(5), Guo‐Liang Lu(4), Fernando Doñate(4), William R. Wilson(4), Fanying Meng(4)