Brian Dougherty

AstraZeneca (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index30.6kcitations226works3.52yr avg
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Research Topics

Cancer Genomics and Diagnostics(44), PARP inhibition in cancer therapy(42), CRISPR and Genetic Engineering(36), BRCA gene mutations in cancer(33), Lung Cancer Treatments and Mutations(29)

Publications225 total

Phenome-wide analysis of copy number variants in 470,727 UK Biobank genomes
Nature·2026Open Access
Corrigendum to “Glucagon-like Peptide 1 Agonist Use in an Adult With Cystic Fibrosis–Related Diabetes and Metabolic Syndrome”
AACE Endocrinology and Diabetes·2026
Supplementary Data 1 from Phase I Study of Acalabrutinib Plus Danvatirsen (AZD9150) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma Including Circulating Tumor DNA Biomarker Assessment
2025Open Access
Figure 4 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
2025Open Access
Figure 2 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
2025Open Access
Table 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
2025Open Access
Figure 3 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
2025Open Access
Figure 5 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
2025Open Access
Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
2025Open Access
Comprehensive comparison of enzymatic and bisulfite DNA methylation analysis in clinically relevant samples
Clinical Epigenetics·2025· 2 citedOpen Access
Cell lysis plus depletion single-nucleus RNA-seq (CL-D snRNAseq) v1
2025Open Access
Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer
Nature Communications·2025· 7 citedOpen Access
Glucagon-Like Peptide 1 Agonist Use in an Adult With Cystic Fibrosis–Related Diabetes and Metabolic Syndrome
AACE Endocrinology and Diabetes·2025· 1 citedOpen Access
Comprehensive cellular analysis with single-nucleus RNA-seq of archived PAXgene whole blood samples
2025Open Access
Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases
Nature Communications·2025· 7 citedOpen Access
Somatic BRCA1/2 mutations are associated with a similar survival advantage to their germline counterparts in tubo-ovarian high grade serous carcinoma
European Journal of Cancer·2025· 8 citedOpen Access
Molecular Profiling Identifies CD49d and CD79b as Predictive Markers for Acquired Acalabrutinib Resistance in Patients With Chronic Lymphocytic Leukemia
Hematological Oncology·2024· 3 citedOpen Access
Data from Phase 1 Study of Acalabrutinib Plus Danvatirsen (AZD9150) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma Including Circulating Tumor DNA Biomarker Assessment
2024Open Access
Supplementary Data 1 from Phase 1 Study of Acalabrutinib Plus Danvatirsen (AZD9150) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma Including Circulating Tumor DNA Biomarker Assessment
2024Open Access
Supplementary Data 1 from Phase 1 Study of Acalabrutinib Plus Danvatirsen (AZD9150) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma Including Circulating Tumor DNA Biomarker Assessment
2024Open Access
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Frequent Co-authors

J. Carl Barrett(14), Hamilton O. Smith(12), J. Craig Venter(12), Zhongwu Lai(12), Claire M. Fraser(11), Robert Fleischmann(10), William Nelson(10), Mark D. Adams(8), Rebecca A. Clayton(8), Anthony R. Kerlavage(8), Matthew Cotton(8), Teresa R. Utterback(8), Owen White(8), Robert J. Dodson(8), Jeremy Peterson(8), Jean-François Tomb(7), Janice F. Weidman(7), Karen A. Ketchum(7), Erin K. Hickey(7), Ewen F. Kirkness(6)