Martin van der Laan

Saarland University — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

57h-index8.8kcitations127works2.82yr avg
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Research Topics

Mitochondrial Function and Pathology(96), ATP Synthase and ATPases Research(78), Metabolism and Genetic Disorders(29), RNA and protein synthesis mechanisms(26), RNA modifications and cancer(12)

Publications127 total

Mitochondrial contact site and cristae organizing system promotes modular assembly of cytochrome c oxidase
Cell Reports·2025Open Access
Structural studies suggest CCDC127 as a novel membrane contact site protein in the mitochondrial intermembrane space
2025Open Access
Topology control by a conserved cysteine pair in the OMM-protein CCDC127 enables MICOS interaction
2025· 1 citedOpen Access
A multiplexed approach for genetic screening of human cells by electron microscopy uncovers a critical effector of mitochondrial cristae shape
2025· 1 citedOpen Access
Adaptive mechanisms in pancreatic islets counteract mitochondrial dysfunction in Barth syndrome
Diabetologia·2025Open Access
MICOS
Current Biology·2025
Molecular machineries shaping the mitochondrial inner membrane
Nature Reviews Molecular Cell Biology·2025· 18 cited
Coordination of cytochrome bc1 complex assembly at MICOS
EMBO Reports·2024· 5 citedOpen Access
Proteinimport über die mitochondriale Innenmembran
BIOspektrum·2024Open Access
Pancreatic islets undergo functional and morphological adaptation during development of Barth Syndrome
2024Open Access
Identification of MIMAS, a multifunctional mega-assembly integrating metabolic and respiratory biogenesis factors of mitochondria
Cell Reports·2024· 6 citedOpen Access
Coordination of cytochrome <i>bc</i> <sub>1</sub> complex assembly at MICOS
2024· 2 citedOpen Access
Structural mechanism of mitochondrial membrane remodelling by human OPA1
Nature·2023· 101 citedOpen Access
Central role of Tim17 in mitochondrial presequence protein translocation
Nature·2023· 52 citedOpen Access
Structural insights into crista junction formation by the Mic60-Mic19 complex
Science Advances·2022· 44 citedOpen Access
Coupling to Pam16 differentially controls the dual role of Pam18 in protein import and respiratory chain formation
Cell Reports·2022· 17 citedOpen Access
Structural insights into crista junction formation by the Mic60-Mic19 complex
2022· 1 citedOpen Access
Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth
Cell Reports·2022· 38 citedOpen Access
Targeted Lipidomics of Mitochondria in a Cellular Alzheimer’s Disease Model
Biomedicines·2021· 17 citedOpen Access
Hexokinases inhibit death receptor–dependent apoptosis on the mitochondria
Proceedings of the National Academy of Sciences·2021· 45 citedOpen Access
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Frequent Co-authors

Nikolaus Pfanner(32), Maria Bohnert(19), Peter Rehling(15), Nils Wiedemann(14), Bernard Guiard(14), Bettina Warscheid(12), Ralf M. Zerbes(10), Silke Oeljeklaus(9), Thomas Becker(9), Agnieszka Chacińska(9), Karina von der Malsburg(6), Dana P. Hutu(6), Chris Meisinger(6), Ida J. van der Klei(6), Michael Gebert(5), Sebastian Wiese(5), Helmut E. Meyer(5), Marten Veenhuis(5), Inge Perschil(5), Susanne E. Horvath(5)