James L. Hedrick

IBM Research - Almaden — United States

Materials Science · Physical Sciences

109h-index39.6kcitations513works7.42yr avg
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Research Topics

biodegradable polymer synthesis and properties(147), Advanced Polymer Synthesis and Characterization(115), Synthesis and properties of polymers(111), Synthetic Organic Chemistry Methods(89), Carbon dioxide utilization in catalysis(87)

Publications513 total

Replacing PEG-Lipid with Amphiphilic Polycarbonates in mRNA-Loaded Lipid Nanoparticles: Impact of Polycarbonate Structure on Physicochemical and Transfection Properties
Biomacromolecules·2025· 1 cited
Photopolymer Resins from Sulfenyl Chloride Commodity Chemicals for Plastic Optics, Photopatterning and 3D‐Printing
Advanced Materials·2025· 6 citedOpen Access
High-throughput computational analysis of kinetic barriers to ring-closing depolymerization for aliphatic polycarbonates
2025Open Access
Rapid Functionalization of Polycarbonates and Polyurethanes via Organocatalyzed SNAr
2024Open Access
Highly Selective <i>O</i>-Phenylene Bisurea Catalysts for ROP: Stabilization of Oxyanion Transition State by a Semiflexible Hydrogen Bond Pocket
Journal of the American Chemical Society·2024· 15 cited
Cyclopropenimine‐Mediated CO<sub>2</sub> Activation for the Synthesis of Polyurethanes and Small‐Molecule Carbonates and Carbamates
Angewandte Chemie International Edition·2024· 15 citedOpen Access
Cyclopropenimine‐Mediated CO<sub>2</sub> Activation for the Synthesis of Polyurethanes and Small‐Molecule Carbonates and Carbamates
Angewandte Chemie·2024· 4 citedOpen Access
Ring-Opening Polymerization of Cyclic Esters and Carbonates with (Thio)urea/Cyclopropenimine Organocatalytic Systems
ACS Macro Letters·2024· 18 cited
Contrasting Roles of Counterions in Anionic Ring-Opening Polymerization Mediated by Heterocycle Organocatalysts
ACS Catalysis·2023· 10 cited
pH-Responsive Polymeric Micelle Dynamic Complexes for Selective Killing of <i>Helicobacter pylori</i>
Biomacromolecules·2023· 12 cited
Amphiphilic Sulfonated Polycarbonates Inactivate SARS-CoV-2 in Seconds
Macromolecules·2023· 5 cited
Author Correction: Artificial intelligence driven design of catalysts and materials for ring opening polymerization using a domain-specific language
Nature Communications·2023· 1 citedOpen Access
Artificial intelligence driven design of catalysts and materials for ring opening polymerization using a domain-specific language
Nature Communications·2023· 30 citedOpen Access
Nanocomplexes of Biodegradable Anticancer Macromolecules: Prolonged Plasma Half‐Life, Reduced Toxicity, and Increased Tumor Targeting
Advanced Healthcare Materials·2023· 8 citedOpen Access
An extensible platform for enabling artificial intelligence guided design of catalysts and materials
2023· 3 citedOpen Access
An extensible software platform for accelerating polymer discovery through informatics and artificial intelligence development
2022· 5 citedOpen Access
A Cation-Dependent Dual Activation Motif for Anionic Ring-Opening Polymerization of Cyclic Esters
Journal of the American Chemical Society·2022· 27 cited
Simple and Efficient Synthesis of Functionalized Cyclic Carbonate Monomers Using Carbon Dioxide
ACS Macro Letters·2022· 34 cited
Synthesis of Tailored Segmented Polyurethanes Utilizing Continuous-Flow Reactors and Real-Time Process Monitoring
Chemistry of Materials·2021· 15 cited
Author Correction: Accelerated antimicrobial discovery via deep generative models and molecular dynamics simulations
Nature Biomedical Engineering·2021· 9 citedOpen Access
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Frequent Co-authors

Robert M. Waymouth(19), Craig J. Hawker(11), Russell C. Pratt(10), Bas G. G. Lohmeijer(7), David Mecerreyes(7), Fredrik Nederberg(7), Chuan Yang(6), Philippe Dúbois(6), Andrew P. Dove(5), Charles G. Wade(5), Yi‐Yan Yang(5), Yi Yan Yang(5), Eric F. Connor(4), G.W. Nyce(4), Mikael Trollsås(4), Eva Malmström(3), David A. Long(3), Kazuki Fukushima(3), Zhan Yuin Ong(3), Hans W. Horn(3)