Knut Biber

AbbVie (Germany) — Germany

Neuroscience · Life Sciences

13h-index2.8kcitations55works18.82yr avg
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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms(27), Alzheimer's disease research and treatments(13), Immune cells in cancer(8), Chemokine receptors and signaling(8), Neurological Disease Mechanisms and Treatments(6)

Publications55 total

Exploring the Aβ Plaque Microenvironment in Alzheimer’s Disease Model Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer
Pharmaceuticals·2025· 4 citedOpen Access
Exploring the Aβ Plaque Microenvironment in Alzheimer’s Disease Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer
2024Open Access
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease
Nature Neuroscience·2024· 59 citedOpen Access
Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer’s disease reveals distinct sequential responses to Aβ and tau
Acta Neuropathologica·2024· 12 citedOpen Access
Depletion of microglia with CSF1R inhibitor prevents tau aggregation in the mouse model Thy1P301S
Alzheimer s & Dementia·2023Open Access
Distinct transcriptomic responses to Aβ plaques, neurofibrillary tangles, and <i>APOE</i> in Alzheimer's disease
Alzheimer s & Dementia·2023· 38 citedOpen Access
Microglia show distinct tau associated subpopulations along tau spreading in human Alzheimer’s disease
Alzheimer s & Dementia·2023Open Access
The <i>APOE</i>ε4 allele exacerbates the transcriptomic responses to Aβ plaques and neurofibrillary tangles in Alzheimer’s disease
Alzheimer s & Dementia·2023· 1 citedOpen Access
Distinct Transcriptomic Responses to Aβ plaques, Neurofibrillary Tangles, and <i>APOE</i> in Alzheimer’s Disease
2023· 3 citedOpen Access
Endothelial Cells are Heterogeneous in Different Brain Regions and are Dramatically Altered in Alzheimer’s Disease
2023· 7 citedOpen Access
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease
2022· 4 citedOpen Access
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease
2022· 10 citedOpen Access
Microglia states and nomenclature: A field at its crossroads
Neuron·2022· 1.7k citedOpen Access
Defining Microglial States and Nomenclature: A Roadmap to 2030
SSRN Electronic Journal·2022· 32 citedOpen Access
Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease
Acta Neuropathologica·2021· 434 citedOpen Access
ABACUS: A flexible UMI counter that leverages intronic reads for single-nucleus RNAseq analysis
2020· 7 citedOpen Access
Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue
Frontiers in Molecular Neuroscience·2020· 80 citedOpen Access
Detection of Synaptic Proteins in Microglia by Flow Cytometry
Frontiers in Molecular Neuroscience·2020· 28 citedOpen Access
Profiling microglia from AD donors and non-demented elderly in acute human post-mortem cortical tissue
2020· 10 citedOpen Access
Microglial Drug Targets in AD: Opportunities and Challenges in Drug Discovery and Development
Frontiers in Pharmacology·2019· 34 citedOpen Access
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Frequent Co-authors

Maya E. Woodbury(13), Astrid Wachter(10), Robert V. Talanian(10), Alberto Serrano‐Pozo(9), Bradley T. Hyman(9), Sudeshna Das(9), Joseph A. Tamm(8), Eric Karran(8), Zhaozhi Li(7), Aicha Abdourahman(7), Nieske Brouwer(6), Ayush Noori(6), Gen Lin(6), Taekyung Kwon(6), Rachel E. Bennett(6), Hendrikus Boddeke(6), Erik Boddeke(5), Bart J. L. Eggen(5), Fan Liao(5), Timothy Pastika(5)