Thomas Liechti

National Institutes of Health — United States

Immunology and Microbiology · Life Sciences

16h-index715citations42works1.22yr avg
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Research Topics

Immune Cell Function and Interaction(20), T-cell and B-cell Immunology(14), HIV Research and Treatment(10), Monoclonal and Polyclonal Antibodies Research(9), Single-cell and spatial transcriptomics(6)

Publications42 total

Novel Spectral High‐Dimensional Flow Cytometry Assay for Combinatorial <scp>MHC</scp> Class I Tetramer Staining and Deep Antigen‐Specific <scp>CD8</scp>+ T Cell Phenotyping
Cytometry Part A·2025
Infection with Mycobacterium tuberculosis alters the antibody response to HIV-1
PLoS Pathogens·2025· 1 citedOpen Access
Cytotoxic Signature and <scp>IFN</scp>‐γ Production Dominate <scp>CD4</scp><sup>+</sup> T‐Cell Response During Human Toxoplasmosis
Immunology·2025· 2 citedOpen Access
Potential and challenges of clinical high‐dimensional flow cytometry: A call to action
Cytometry Part A·2024· 3 citedOpen Access
Author response for "Potential and challenges of clinical high‐dimensional flow cytometry: A call to action"
2024
Signatures of CD4+ T and B cells are associated with distinct stages of chronic chagasic cardiomyopathy
Frontiers in Immunology·2024· 1 citedOpen Access
A robust pipeline for high-content, high-throughput immunophenotyping reveals age- and genetics-dependent changes in blood leukocytes
Cell Reports Methods·2023· 14 citedOpen Access
OA-50 Pharmacodynamic effects of tiragolumab, as monotherapy and in combos with daratumumab and atezolizumab in patients with R/R MM: biomarker results from a phase 1a/1b trial
Clinical Lymphoma Myeloma & Leukemia·2023
PS-P13-6: DEFINING THE RELATIONSHIP BETWEEN IMMUNE TRAITS AND LIPIDS IN TWINSUK
Journal of Hypertension·2023
Chagasic cardiomyopathy is marked by a unique signature of activated CD4+ T cells
Journal of Translational Medicine·2022· 9 citedOpen Access
Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples
Nature Communications·2022· 28 citedOpen Access
Phage display of environmental protein toxins and virulence factors reveals the prevalence, persistence, and genetics of antibody responses
Immunity·2022· 37 citedOpen Access
Immune phenotypes that predict COVID-19 severity
2022· 4 citedOpen Access
Analysis of antibody binding specificities in twin and SNP-genotyped cohorts reveals that antiviral antibody epitope selection is a heritable trait
Immunity·2022· 36 citedOpen Access
Systematic identification of genomic elements that regulate<i>FCGR2A</i>expression and harbor variants linked with autoimmune disease
Human Molecular Genetics·2021· 15 citedOpen Access
Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization
Nature Communications·2021· 18 citedOpen Access
Prevalence, persistence, and genetics of antibody responses to protein toxins and virulence factors
2021· 4 citedOpen Access
Defining the relationship between lipids and immune traits in TwinsUK
European Heart Journal·2021
An updated guide for the perplexed: cytometry in the high-dimensional era
Nature Immunology·2021· 89 cited
OMIP 074: Phenotypic analysis of <scp>IgG</scp> and <scp>IgA</scp> subclasses on human B cells
Cytometry Part A·2021· 5 citedOpen Access
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Frequent Co-authors

Mario Roederer(21), Huldrych F. Günthard(12), Alexandra Trkola(12), Massimo Mangino(9), Roger D. Kouyos(7), Claus Kadelka(7), Tim D. Spector(7), Margaret H. Beddall(6), Michael Huber(5), Nikolas Friedrich(5), Thiagarajan Venkataraman(5), H. Benjamin Larman(5), Peter Rusert(4), Hanna Ebner(4), Merle Schanz(4), Dominique L. Braun(4), Enos Bernasconi(4), Alexandra Calmy(4), Jürg Böni(4), Cristian Valencia(4)