Gordon C. Weir

Joslin Diabetes Center — United States

Medicine · Health Sciences

103h-index36.8kcitations419works1.52yr avg
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Research Topics

Pancreatic function and diabetes(356), Diabetes and associated disorders(187), Diabetes Management and Research(151), Metabolism, Diabetes, and Cancer(71), Diabetes Treatment and Management(53)

Publications408 total

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas
Journal of Visualized Experiments·2025
Renalase inhibition defends against acute and chronic β cell stress by regulating cell metabolism
Molecular Metabolism·2025· 4 citedOpen Access
Renalase inhibition regulates β cell metabolism to defend against acute and chronic stress
2024Open Access
Enhancement of Subcutaneous Islet Transplant Performance by Collagen 1 Gel
Cell Transplantation·2024· 2 citedOpen Access
Conflicting Views About Interactions Between Pancreatic α-Cells and β-Cells
Diabetes·2023· 21 citedOpen Access
C-peptide and metabolic outcomes in trials of disease modifying therapy in new-onset type 1 diabetes: an individual participant meta-analysis
The Lancet Diabetes & Endocrinology·2023· 45 citedOpen Access
Induction of remission in diabetes by lowering blood glucose
Frontiers in Endocrinology·2023· 9 citedOpen Access
Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response
Science Advances·2023· 21 citedOpen Access
Islet Inflammation Can Be Linked to the Disruption of Proinsulin Processing in Type 1 Diabetes but not in Type 2 Diabetes
The Journal of Clinical Endocrinology & Metabolism·2022· 4 citedOpen Access
The β-cell glucose toxicity hypothesis: Attractive but difficult to prove
Metabolism·2021· 27 citedOpen Access
Reduced glucose-induced first-phase insulin release is a danger signal that predicts diabetes
Journal of Clinical Investigation·2021· 16 citedOpen Access
Why pancreatic islets should be regarded and regulated like organs.
PubMed·2021· 6 citedOpen Access
A novel cellular engineering approach to diabetes mellitus
Nature Reviews Endocrinology·2020· 2 cited
Review for "Pre‐clinical evaluation of <scp>TYK2</scp> inhibitors for human beta cell protection in type 1 diabetes"
2020
β-cell secretory dysfunction: a key cause of type 2 diabetes – Authors' reply
The Lancet Diabetes & Endocrinology·2020· 5 citedOpen Access
A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells
Nature Biomedical Engineering·2020· 156 citedOpen Access
Beta cell identity changes with mild hyperglycemia: Implications for function, growth, and vulnerability
Molecular Metabolism·2020· 74 citedOpen Access
Inadequate β-cell mass is essential for the pathogenesis of type 2 diabetes
The Lancet Diabetes & Endocrinology·2020· 189 citedOpen Access
Glucolipotoxicity, β-Cells, and Diabetes: The Emperor Has No Clothes
Diabetes·2019· 164 citedOpen Access
Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations
Nature Materials·2019· 171 citedOpen Access
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Frequent Co-authors

Susan Bonner‐Weir(28), Arun Sharma(9), Hideaki Kaneto(6), Arturo J. Vegas(5), Jennifer Hollister‐Lock(5), Daniel G. Anderson(5), D. Ross Laybutt(5), Omid Veiseh(4), Joshua C. Doloff(4), Andrew Bader(4), Matthew A. Bochenek(4), Michael Chen(4), José Oberholzer(4), Dale L. Greiner(4), Róbert Langer(4), Hok Hei Tam(3), Erin Langan(3), Siddharth Jhunjhunwala(3), Stephanie Aresta-Dasilva(3), Meirigeng Qi(3)