Roberta Chiaraluce

Materials Science · Physical Sciences

23h-index2.0kcitations85works27.02yr avg
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Research Topics

Enzyme Structure and Function(30), Amino Acid Enzymes and Metabolism(17), Protein Structure and Dynamics(16), Heat shock proteins research(7), Enzyme Production and Characterization(7)

Publications84 total

Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges
Human Genetics·2025Open Access
The complex impact of cancer-related missense mutations on the stability and on the biophysical and biochemical properties of MAPK1 and MAPK3 somatic variants
Human Genomics·2023· 9 citedOpen Access
Mutation in the Common Docking Domain Affects MAP Kinase ERK2 Catalysis and Stability
Cancers·2023· 7 citedOpen Access
Interpretation of Missense Variants Found in Association with Cancer
Encyclopedia of Life Sciences·2023
The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin
The European Physical Journal Plus·2023· 4 citedOpen Access
Metal Ion Binding in Wild-Type and Mutated Frataxin: A Stability Study
Frontiers in Molecular Biosciences·2022Open Access
Zn‐Induced Interactions Between SARS‐CoV‐2 orf7a and BST2/Tetherin
ChemistryOpen·2021· 18 citedOpen Access
A Glimpse into the Structural Properties of the Intermediate and Transition State in the Folding of Bromodomain 2 Domain 2 by Φ Value Analysis
International Journal of Molecular Sciences·2021· 1 citedOpen Access
Analysis and Interpretation of the Impact of Missense Variants in Cancer
International Journal of Molecular Sciences·2021· 76 citedOpen Access
Evaluating the predictions of the protein stability change upon single amino acid substitutions for the FXN CAGI5 challenge
Human Mutation·2019· 19 citedOpen Access
Dealing with Cu reduction in X-ray absorption spectroscopy experiments
Metallomics·2019· 12 cited
Characterization of human frataxin missense variants in cancer tissues
Human Mutation·2019· 21 citedOpen Access
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme
PLoS ONE·2018· 27 citedOpen Access
Unveiling the folding mechanism of the Bromodomains
Biochemistry and Biophysics Reports·2017· 1 citedOpen Access
The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process
Biophysical Chemistry·2017· 19 cited
Single-Nucleotide Polymorphism of PPARγ, a Protein at the Crossroads of Physiological and Pathological Processes
International Journal of Molecular Sciences·2017· 14 citedOpen Access
PEGylated β‐Sheet Breaker Peptides as Inhibitors of β‐Amyloid Fibrillization
ChemPlusChem·2016· 5 cited
Production of functional, stable, unmutated recombinant human papillomavirus E6 oncoprotein: implications for HPV-tumor diagnosis and therapy
Journal of Translational Medicine·2016· 15 citedOpen Access
Effect of BET Missense Mutations on Bromodomain Function, Inhibitor Binding and Stability
PLoS ONE·2016· 18 citedOpen Access
Crystal structure of the second bromodomain Q443H mutant of human BRD2
2016
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Frequent Co-authors

Valerio Consalvi(44), Alessandra Pasquo(15), Roberto Scandurra(9), Maria Petrosino(9), Laura Politi(8), Mario De Rosa(6), R Scandurra(5), Velia Minicozzi(5), Silvia Morante(5), Simonetta Stefanini(5), Clorinda Lori(5), Cesare Giordano(4), Giancarlo Rossi(4), Emidio Capriotti(4), Francesco Bossa(4), Stefan Knapp(4), Emilia Chiancone(4), Andrea Ilari(4), Leonore Novak(3), Paola Turina(3)