Claire Hull

TauRx (United Kingdom) — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index854citations20works0.72yr avg
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Research Topics

Genetics and Neurodevelopmental Disorders(8), Autism Spectrum Disorder Research(7), Alzheimer's disease research and treatments(6), Neuroinflammation and Neurodegeneration Mechanisms(3), Neuroscience and Neuropharmacology Research(2)

Publications20 total

Clinical, imaging and blood biomarker outcomes in a Phase 3 clinical trial of tau aggregation inhibitor hydromethylthionine mesylate in mild cognitive impairment and mild to moderate dementia due to Alzheimer’s disease
The Journal of Prevention of Alzheimer s Disease·2026Open Access
Hydromethylthionine sustains truncated tau‐dependent inflammation‐lowering effects in mouse brain
FEBS Journal·2025· 2 citedOpen Access
Author response for "Hydromethylthionine sustains truncated tau‐dependent inflammation‐lowering effects in mouse brain"
2024
Exploring the Anti-Hypoxaemia Effect of Hydromethylthionine: A Prospective Study of Phase 3 Clinical Trial Participants
International Journal of Molecular Sciences·2023Open Access
Neurochemical, histological, and behavioral profiling of the acute, sub‐acute, and chronic <scp>MPTP</scp> mouse model of Parkinsonʼs disease
Journal of Neurochemistry·2022· 33 citedOpen Access
Apolipoprotein E loss of function: Influence on murine brain markers of physiology and pathology
Aging Brain·2022· 7 citedOpen Access
The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2021· 18 cited
NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia
Neuropharmacology·2020· 31 citedOpen Access
Knock-in of Mutated hTAU Causes Insulin Resistance, Inflammation and Proteostasis Disturbance in a Mouse Model of Frontotemporal Dementia
Molecular Neurobiology·2019· 21 citedOpen Access
Effects of Liraglutide and Fenretinide treatments on the diabetic phenotype of neuronal human BACE1 knock-in mice
Biochemical Pharmacology·2019· 10 citedOpen Access
Metabolic and cellular phenotypes in a PLB mouse model of dementia
2019
Distinctive temporal profiles of detergent-soluble and -insoluble tau and Aβ species in human Alzheimer’s disease
Brain Research·2018· 23 cited
Emotional and neurocognitive deficits in fragile X
American Journal of Medical Genetics·1994· 74 cited
Evaluation of school children at high risk for fragile X syndrome utilizing buccal cell FMR‐1 testing
American Journal of Medical Genetics·1994· 49 cited
Obstetrical and gynecological complications in fragile X carriers: A multicenter study
American Journal of Medical Genetics·1994· 205 cited
High functioning fragile X males: Demonstration of an unmethylated fully expanded FMR‐1 mutation associated with protein expression
American Journal of Medical Genetics·1994· 223 cited
Symptoms of Schizotypal Personality Disorder in Fragile X Women
Journal of the American Academy of Child & Adolescent Psychiatry·1994· 74 cited
A Study of the Physical, Behavioral, and Medical Phenotype, Including Anthropometric Measures, of Females With Fragile X Syndrome
Archives of Pediatrics and Adolescent Medicine·1993· 60 cited
Analysis of mutations at the fragile X locus using the DNA probe Ox1.9
American Journal of Medical Genetics·1992· 24 cited
The rett syndrome bibliography III, 1989
Brain and Development·1990

Frequent Co-authors

Bettina Platt(7), Randi J. Hagerman(6), Mirela Delibegović(5), Gernot Riedel(4), Ruta Dekeryte(4), Heather Buchanan(4), Sarah Kamli-Salino(3), Charles R. Harrington(3), Louise W. Staley(2), Karen Snow(2), Annette K. Taylor(2), William E. Sobesky(2), David J. Koss(2), Renato X. Santos(2), Sophie H. Lee(2), Richard Lofthouse(2), Valeria Melis(2), Lianne Robinson(2), Michael Leith(2), Eline Dreesen(2)