Vincent Denis

Beth Israel Deaconess Medical Center — United States

Medicine · Health Sciences

11h-index782citations22works1.52yr avg
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Research Topics

Colorectal Cancer Treatments and Studies(5), Cancer therapeutics and mechanisms(4), Cancer Mechanisms and Therapy(4), DNA Repair Mechanisms(3), Monoclonal and Polyclonal Antibodies Research(3)

Publications22 total

Generation Using Phage-Display of pH-Dependent Antibodies Against the Tumor-Associated Antigen AXL
Antibodies·2025Open Access
Pregnancy outcomes with increasing maternal age, greater than 40 years, in donor oocyte cycles
Human Reproduction·2025· 3 cited
Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells
PLoS ONE·2022· 6 citedOpen Access
Antibody targeting of claudin-1 as a potential colorectal cancer therapy
Journal of Experimental & Clinical Cancer Research·2017· 62 citedOpen Access
FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer
British Journal of Cancer·2016· 51 citedOpen Access
Abstract B16: Cetuximab activates Foxo3a via the MAPK p38 to induce apoptosis and reduce cell proliferation in colorectal cancer cells
Molecular Cancer Therapeutics·2015
Abstract B245: Claudin-1 (CLDN1) as a new therapeutic target in colorectal cancer: Inhibition of cell growth and survival by an anti-CLDN1 monoclonal antibody.
Molecular Cancer Therapeutics·2013· 1 cited
Abstract A62: p38MAPK implication in cetuximab response.
Molecular Cancer Therapeutics·2013
Specific In Vivo Labeling of Tyrosinated α-Tubulin and Measurement of Microtubule Dynamics Using a GFP Tagged, Cytoplasmically Expressed Recombinant Antibody
PLoS ONE·2013· 18 citedOpen Access
MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy
Autophagy·2012· 95 citedOpen Access
Selection for intrabody solubility in mammalian cells using GFP fusions
Protein Engineering Design and Selection·2011· 22 citedOpen Access
New Topoisomerase I mutations are associated with resistance to camptothecin
Molecular Cancer·2011· 75 citedOpen Access
Abstract 1639: Targeting the p38 MAPK pathway inhibits irinotecan resistance in colon adenocarcinoma
Cancer Research·2011
Targeting the p38 MAPK Pathway Inhibits Irinotecan Resistance in Colon Adenocarcinoma
Cancer Research·2010· 84 citedOpen Access
R83: Le ciblage de la voie de la MAPK p38 inhibe la chimiorésistance dans le cancer du côlon
Bulletin du Cancer·2010
Abstract 2565: Targeting the p38 MAPK pathway inhibits drug resistance in colon adenocarcinoma cells
Cancer Research·2010
Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38
Cancer Biology & Therapy·2008· 30 citedOpen Access
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells
Molecular Cancer·2008· 199 citedOpen Access
Hydrogen peroxide-induced cell death in normal human keratinocytes is differentiation dependent
Free Radical Biology and Medicine·2004· 64 cited
Induction of somatic hypermutation by antigen‐specific B cell receptors in the human BL2 cell line
European Journal of Immunology·2004· 2 cited
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Frequent Co-authors

Pierre Martineau(17), Maguy Del Rio(14), Céline Gongora(14), Nadia Vezzio-Vié(8), Caroline Mollévi(6), Annick Causse(6), Laetitia Marzi(6), Florence Boissière‐Michot(6), Frédéric Bibeau(5), Eve Combès(5), Christian Larroque(4), Salomé Paillas(4), Adeline Ayrolles-Torro(4), Nadia Vié(3), Nicole Bec(3), Bruno Robert(3), Caroline Fraslon(3), Philippe Pourquier(3), Martine Pugnière(3), Christel Larbouret(3)