Yoshihiro Kubo

The Graduate University for Advanced Studies, SOKENDAI — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

43h-index7.7kcitations293works5.02yr avg
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Research Topics

Ion channel regulation and function(106), Neuroscience and Neuropharmacology Research(62), Cardiac electrophysiology and arrhythmias(51), Receptor Mechanisms and Signaling(51), Neuroscience and Neural Engineering(22)

Publications282 total

Metabotropic glutamate receptors in GtoPdb v.2025.3
IUPHAR/BPS Guide to Pharmacology CITE·2025Open Access
Extracellular K <sup>+</sup> modulates the pore conformations of Cys-loop receptor anion channels
2025
Characterization and Engineering of a Blue-Sensitive, Gi/o-Biased, and Bistable Ciliary Opsin from a Fan Worm
Biochemistry·2025· 3 cited
Characterization and engineering of a blue-sensitive, Gi/o-biased, and bistable ciliary opsin from a fan worm
2024Open Access
Structural determinants of M2R involved in inhibition by Sigma-1R
Journal of Biological Chemistry·2024· 1 citedOpen Access
Structural determinants of the direct inhibition of GIRK channels by Sigma-1 receptor antagonist
Journal of Biological Chemistry·2024· 4 citedOpen Access
Structural determinants of the direct inhibition of GIRK channels by Sigma-1 receptor antagonist
2023Open Access
A self-inactivating invertebrate opsin optically drives biased signaling toward Gβγ-dependent ion channel modulation
Proceedings of the National Academy of Sciences·2023· 19 citedOpen Access
Two single-point mutations in Ankyrin Repeat one drastically change the threshold temperature of TRPV1
Nature Communications·2023· 19 citedOpen Access
Regulation of the two-pore domain potassium channel, THIK-1 and THIK-2, by G protein coupled receptors
PLoS ONE·2023· 8 citedOpen Access
Inwardly rectifying potassium channels (K&lt;sub&gt;IR&lt;/sub&gt;) in GtoPdb v.2023.1
IUPHAR/BPS Guide to Pharmacology CITE·2023· 2 citedOpen Access
Metabotropic glutamate receptors in GtoPdb v.2023.1
IUPHAR/BPS Guide to Pharmacology CITE·2023· 6 citedOpen Access
Congratulations, celebrations, invitations!
The Journal of Physiology·2023· 1 citedOpen Access
Conformational rearrangements in the second voltage sensor domain switch PIP <sub>2</sub> - and voltage-gating modes in two-pore channels
Proceedings of the National Academy of Sciences·2023· 6 citedOpen Access
A self-inactivating invertebrate opsin with resistance to retinal depletion optically drives biased signaling toward Gβγ-dependent ion channel modulation
2023Open Access
Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior
Cell Reports·2022· 26 citedOpen Access
Conformational rearrangements in 2 <sup>nd</sup> voltage sensor domain switch PIP <sub>2</sub> - and voltage-gating modes in two-pore channels
2022· 1 citedOpen Access
Closed-state inactivation of cardiac, skeletal, and neuronal sodium channels is isoform specific
The Journal of General Physiology·2022· 2 citedOpen Access
Promotion of Cyst Formation from a Renal Stem Cell Line Using Organ-Specific Extracellular Matrix Gel Format Culture System
Gels·2022· 1 citedOpen Access
Dopamine Drives Neuronal Excitability via KCNQ Channel Phosphorylation for Reward Behavior
SSRN Electronic Journal·2022· 4 citedOpen Access
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Frequent Co-authors

Osamu Saitoh(8), Koichi Nakajo(6), Michihiro Tateyama(6), Yuichiro Fujiwara(5), Lily Yeh Jan(4), Katsuhiro Nagatomo(4), I‐Shan Chen(4), Yuh Nung Jan(3), Tomoyuki Miyashita(3), Yoshimichi Murata(3), Tomomi M. Yamamoto(3), Mako Kurogi(3), Tomiko Asano(2), Hiroyasu Nakata(2), Kenji Takeuchi(2), Sumalee Boonmar(2), T Katayama(2), Qui-Lim Choo(2), George Kuo(2), Michael Houghton(2)