Denise Sickert

Roche (Switzerland) — Switzerland

Medicine · Health Sciences

11h-index757citations22works5.02yr avg
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Research Topics

CAR-T cell therapy research(7), Monoclonal and Polyclonal Antibodies Research(6), T-cell and B-cell Immunology(5), RNA Interference and Gene Delivery(5), Biosimilars and Bioanalytical Methods(4)

Publications22 total

Latest results from the dose‐expansion part (Part 2) of the Brainshuttle™ AD study of trontinemab in people with Alzheimer’s disease
Alzheimer s & Dementia·2025Open Access
Ocular Pharmacodynamics of Intravitreal Faricimab in Patients With Neovascular Age-Related Macular Degeneration or Diabetic Macular Edema
Translational Vision Science & Technology·2024· 10 citedOpen Access
Supplementary Data from Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia
2023Open Access
Data from Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia
2023Open Access
Data from Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia
2023Open Access
Supplementary Data from Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia
2023Open Access
A cell-based immunogenicity assay to detect antibodies against chimeric antigen receptor expressed by tisagenlecleucel
Journal of Immunological Methods·2019· 20 citedOpen Access
First-in-human clinical trial to assess pharmacokinetics, pharmacodynamics, safety, and tolerability of iscalimab, an anti-CD40 monoclonal antibody
American Journal of Transplantation·2019· 81 cited
Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia
Clinical Cancer Research·2018· 218 citedOpen Access
Nonclinical Safety Assessment of CFZ533, a Fc-Silent Anti-CD40 Antibody, in Cynomolgus Monkeys
Toxicological Sciences·2018· 19 citedOpen Access
Characterization of the in vitro and in vivo properties of CFZ533, a blocking and non-depleting anti-CD40 monoclonal antibody
American Journal of Transplantation·2018· 89 citedOpen Access
Feedback from the European Bioanalysis Forum: Focus Workshop on Current Analysis of Immunogenicity: Best Practices and Regulatory Hurdles
Bioanalysis·2018· 11 citedOpen Access
Non-clinical safety assessment of CFZ533, a Fc-silent anti-CD40 antibody, in non-human primates
2018
CTL019 Clinical Pharmacology and Biopharmaceutics in Pediatric Patients with Relapsed or Refractory (R/R) Acute Lymphoblastic Leukemia (ALL)
Clinical Lymphoma Myeloma & Leukemia·2017· 6 cited
A Novel, Blocking, Fc-Silent Anti-CD40 Monoclonal Antibody Prolongs Nonhuman Primate Renal Allograft Survival in the Absence of B Cell Depletion
American Journal of Transplantation·2015· 77 citedOpen Access
Evaluation of Dried Blood Spots for The Quantification of Therapeutic Monoclonal Antibodies and Detection of Anti-Drug Antibodies
Bioanalysis·2013· 24 cited
Improvement of drug tolerance in immunogenicity testing by acid treatment on Biacore
Journal of Immunological Methods·2008· 57 cited
Characterization of macrophage subpopulations and microvessel density in carcinomas of the gastrointestinal tract.
PubMed·2007· 7 cited
Characterization of macrophage subpopulations in colon cancer using tissue microarrays
Histopathology·2005· 36 cited
Characterization of macrophage subpopulations in colon cancer using tissue microarrays
Pathology - Research and Practice·2004
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Frequent Co-authors

Karen Thudium Mueller(6), Edward Waldron(6), Stephan A. Grupp(6), John E. Levine(6), Theodore W. Laetsch(6), Michael A. Pulsipher(6), Keith J. August(6), Jason S. Hamilton(6), Rakesh Awasthi(6), Abhijit Chakraborty(6), Bruce L. Levine(6), Carl H. June(6), Lori Tomassian(6), Mimi Leung(6), Tetiana Taran(6), Patricia A. Wood(6), Shannon L. Maude(6), Michael W. Boyer(5), Andrew M. Stein(5), Sweta Shah(5)