Jiřı́ Paleček

Czech Academy of Sciences — Czech Republic

Medicine · Health Sciences

31h-index3.0kcitations121works2.22yr avg
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Research Topics

Pain Mechanisms and Treatments(41), Ion Channels and Receptors(14), Neuroscience and Neuropharmacology Research(13), Ion channel regulation and function(12), Fluorine in Organic Chemistry(11)

Publications121 total

Glial Activation Enhances Spinal TRPV1 Receptor Sensitivity in a Paclitaxel Model of Neuropathic Pain
Physiological Research·2025· 1 citedOpen Access
20:4-NAPE induced changes of mechanical sensitivity and DRG neurons excitability are concentration dependent and mediated via NAPE-PLD
Scientific Reports·2025Open Access
Anandamide-Mediated Modulation of Nociceptive Transmission at the Spinal Cord Level
Physiological Research·2024· 5 citedOpen Access
Dual effect of anandamide on spinal nociceptive transmission in control and inflammatory conditions
Biomedicine & Pharmacotherapy·2024· 4 citedOpen Access
The Zn Influence on Degradation Behaviour of Sn-based Materials
Metal ...·2024· 1 citedOpen Access
THE ROLE OF GABAB REGULATORY PROTEIN KCTD16 IN PAIN MODULATION
IBRO Neuroscience Reports·2023Open Access
DUVELISIB, PI3K-DELTA/GAMMA INHIBITOR, PRETREATMENT ATTENUATES BORTEZOMIB-INDUCED NEUROPATHIC PAIN.
IBRO Neuroscience Reports·2023Open Access
Inhibition of synaptic transmission by anandamide precursor 20:4-NAPE is mediated by TRPV1 receptors under inflammatory conditions
Frontiers in Molecular Neuroscience·2023· 4 citedOpen Access
Chemokine CCL2 prevents opioid-induced inhibition of nociceptive synaptic transmission in spinal cord dorsal horn
Journal of Neuroinflammation·2021· 13 citedOpen Access
Hypersensitivity Induced by Intrathecal Bradykinin Administration Is Enhanced by N-oleoyldopamine (OLDA) and Prevented by TRPV1 Antagonist
International Journal of Molecular Sciences·2021· 10 citedOpen Access
Spinal PAR2 Activation Contributes to Hypersensitivity Induced by Peripheral Inflammation in Rats
International Journal of Molecular Sciences·2021· 13 citedOpen Access
Losartan attenuates neuroinflammation and neuropathic pain in paclitaxel‐induced peripheral neuropathy
Journal of Cellular and Molecular Medicine·2020· 55 citedOpen Access
PI3K inhibition reduces mechanical allodynia and sensitization of spinal TRPV1 receptors in a model of paclitaxel-induced painful neuropathy
IBRO Reports·2019Open Access
Losartan treatment attenuates the development of neuropathic thermal hyperalgesia induced by peripheral nerve injury in rats
Life Sciences·2019· 12 cited
Mechanical allodynia and enhanced responses to capsaicin are mediated by PI3K in a paclitaxel model of peripheral neuropathy
Neuropharmacology·2018· 29 cited
The NAv1.7 blocker protoxin II reduces burn injury-induced spinal nociceptive processing
Journal of Molecular Medicine·2017· 16 citedOpen Access
TRPV1 Receptors Contribute to Paclitaxel-Induced c-Fos Expression in Spinal Cord Dorsal Horn Neurons
Physiological Research·2017· 21 citedOpen Access
Peripheral inflammation affects modulation of nociceptive synaptic transmission in the spinal cord induced by N‐arachidonoylphosphatidylethanolamine
British Journal of Pharmacology·2017· 14 citedOpen Access
Hypersensitivity Induced by Activation of Spinal Cord PAR2 Receptors Is Partially Mediated by TRPV1 Receptors
PLoS ONE·2016· 18 citedOpen Access
The Role of Protease-Activated Receptor Type 2 in Nociceptive Signaling and Pain
Physiological Research·2016· 36 citedOpen Access
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Frequent Co-authors

William D. Willis(13), V. Palečková(12), Diana Spicarova(11), Patrick M. Dougherty(8), Pavel Adámek(7), Petra Mrózková(7), Nataliia Kalynovska(4), Susan M. Carlton(3), Vladimír Nerandžič(3), Oldřich Paleta(3), Geertje A. Ubbels(2), Mickaël Diallo(2), Bohumil Dolenský(2), Jaroslav Kvı́čala(2), Mario Heles(2), R. Vejsada(2), P Hník(2), I. Nagy(2), LS Sorkin(1), W. H. Willis(1)