Frédéric H.‐T. Allain

ETH Zurich — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

75h-index18.5kcitations297works71.52yr avg
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Research Topics

RNA Research and Splicing(154), RNA and protein synthesis mechanisms(149), RNA modifications and cancer(101), RNA regulation and disease(26), Enzyme Structure and Function(18)

Publications297 total

Multiplexed Analysis of Multicomponent Biomolecular Condensates without Any Tag
Journal of the American Chemical Society·2025Open Access
Water-detected NMR allows dynamic observations of repeat-expansion RNA condensates
Nature Chemistry·2025· 2 citedOpen Access
Multiplexed analysis of multicomponent biomolecular condensates without any tag
2025Open Access
A highly sensitive protein-RNA cross-linking mass spectrometry workflow with enhanced structural modeling potential
Nucleic Acids Research·2025· 3 citedOpen Access
LLPS REDIFINE allows the biophysical characterization of multicomponent condensates without tags or labels
Nature Communications·2025· 12 citedOpen Access
Newton’s cradle-like allosteric mechanism explains regulatory RsmE RNA binding
2025Open Access
High-throughput screen of 100 000 small molecules in C9ORF72 ALS neurons identifies spliceosome modulators that mobilize G4C2 repeat RNA into nuclear export and repeat associated non-canonical translation
Nucleic Acids Research·2025· 6 citedOpen Access
Volume buffering in multi-component phase separation
2025· 2 citedOpen Access
Steering research on mRNA splicing in cancer towards clinical translation
Nature reviews. Cancer·2024· 30 citedOpen Access
The molecular dissection of TRIM25’s RNA-binding mechanism provides key insights into its antiviral activity
Nature Communications·2024· 21 citedOpen Access
LLPS REDIFINE allows the biophysical characterization of multicomponent condensates without tags or labels
2024
N-terminal domain of polypyrimidine-tract binding protein is a dynamic folding platform for adaptive RNA recognition
Nucleic Acids Research·2024· 2 citedOpen Access
Buffer choice and pH strongly influence phase separation of SARS-CoV-2 nucleocapsid with RNA
Molecular Biology of the Cell·2024· 13 citedOpen Access
The diversity of splicing modifiers acting on A-1 bulged 5′-splice sites reveals rules for rational drug design
Nucleic Acids Research·2024· 17 citedOpen Access
Initial Primer Synthesis of a DNA Primase Monitored by Real-Time NMR Spectroscopy
Journal of the American Chemical Society·2024Open Access
A solid beta-sheet structure is formed at the surface of FUS droplets during aging
Nature Chemical Biology·2024· 77 citedOpen Access
Specific protein-RNA interactions are mostly preserved in biomolecular condensates
Science Advances·2024· 28 citedOpen Access
Ensemble structure of the N-terminal domain (1–267) of FUS in a biomolecular condensate
Biophysical Journal·2024· 12 citedOpen Access
The 100-protein NMR spectra dataset: A resource for biomolecular NMR data analysis
Scientific Data·2024· 12 citedOpen Access
The diversity of splicing modifiers acting on A -1 bulged 5 -splice sites reveals rules for rational drug design
SPIRE - Sciences Po Institutional REpository·2024· 1.2k citedOpen Access
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Frequent Co-authors

Antoine Cléry(12), Cyril Dominguez(5), Gerrit M. Daubner(5), Mario Schubert(5), Florian C. Oberstrass(5), Christophe Maris(4), Sigrid Auweter(4), Richard Štefl(4), Lenka Skříšovská(4), Olivier Duss(4), Sébastien Campagne(3), Douglas L. Black(3), Fred F. Damberger(3), Gabriele Varani(3), Ahmed Moursy(3), Maxim Yulikov(3), Gunnar Jeschke(3), Jonathan Hall(3), Juli Feigon(3), Simon Rüdisser(2)