Gabriel Foley

The University of Queensland — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index894citations39works3.42yr avg
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Research Topics

Genomics and Phylogenetic Studies(11), Fungal Biology and Applications(10), Glycosylation and Glycoproteins Research(5), Pharmacogenetics and Drug Metabolism(4), Machine Learning in Bioinformatics(4)

Publications39 total

Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins
Nature Communications·2025Open Access
Engineering stable and efficient ketol-acid reductoisomerases for industrial biotransformations using ancestral sequence reconstruction.
2025Open Access
Learning the language of phylogeny with MSA Transformer
Cell Systems·2025· 2 cited
Coupling codon and protein constraints decouples drivers of variant pathogenicity
2025· 1 citedOpen Access
Learning the Language of Phylogeny with MSA Transformer
2024· 1 citedOpen Access
Do protein language models learn phylogeny?
Briefings in Bioinformatics·2024· 9 citedOpen Access
Do Protein Language Models Learn Phylogeny?
2024· 6 citedOpen Access
Optimal phylogenetic reconstruction of insertion and deletion events
Bioinformatics·2024· 3 citedOpen Access
Optimal Phylogenetic Reconstruction of Insertion and Deletion Events
2024Open Access
Engineering Biocatalysts for the C−H Activation of Fatty Acids by Ancestral Sequence Reconstruction**
Angewandte Chemie International Edition·2024· 15 citedOpen Access
Engineering Biocatalysts for the C−H Activation of Fatty Acids by Ancestral Sequence Reconstruction**
Angewandte Chemie·2024
Engineering Biocatalysts for the C-H Activation of Fatty Acids using Ancestral Sequence Reconstruction
2023Open Access
Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)
PLoS Computational Biology·2022· 59 citedOpen Access
Ancestral Sequence Reconstruction of a Cytochrome P450 Family Involved in Chemical Defense Reveals the Functional Evolution of a Promiscuous, Xenobiotic-Metabolizing Enzyme in Vertebrates
Molecular Biology and Evolution·2022· 27 citedOpen Access
Methods for ancestral sequence reconstruction of large and complex protein families
2022· 1 cited
Using the Evolutionary History of Proteins to Engineer Insertion-Deletion Mutants from Robust, Ancestral Templates Using Graphical Representation of Ancestral Sequence Predictions (GRASP)
Methods in molecular biology·2021· 19 cited
Structure, function and evolution of the orally active insecticidal toxin complex, YenTc
Acta Crystallographica Section A Foundations and Advances·2021Open Access
Using ancestral sequence reconstruction to create robust highly expressed proteins for crystallography
Acta Crystallographica Section A Foundations and Advances·2021Open Access
Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)
2019· 23 citedOpen Access
NAD <sup>+</sup> cleavage activity by animal and plant TIR domains in cell death pathways
Science·2019· 499 citedOpen Access
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Frequent Co-authors

Mikael Bodén(25), Elizabeth M. J. Gillam(20), Dietmar Haltrich(13), Boštjan Kobe(9), Lachlan W. Casey(7), Daniel J. Ericsson(7), Ian B. Dry(7), Thomas Ve(7), Raine E. S. Thomson(7), S. Horsefield(6), Hayden Burdett(6), M.K. Manik(6), Jonathan Gilley(6), Robert Hughes(6), Todd Bosanac(6), Mark von Itzstein(6), Jeffrey D. Nanson(6), Peter N. Dodds(6), Connie M. Ross(6), Yosephine Gumulya(6)