Francesco Saverio Tedesco

Great Ormond Street Hospital — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index4.1kcitations134works1.92yr avg
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Research Topics

Muscle Physiology and Disorders(62), Tissue Engineering and Regenerative Medicine(41), Pluripotent Stem Cells Research(26), Mesenchymal stem cell research(19), 3D Printing in Biomedical Research(11)

Publications133 total

15OTowards a human multi-organoid platform to develop and assess specificity, toxicity and efficacy of neuromuscular gene therapies
Neuromuscular Disorders·2025
56P3D human iPSC-based modelling of laminopathies to develop gene therapy strategies for LMNA-related congenital muscular dystrophy
Neuromuscular Disorders·2025
Imaging-guided platform for real-time intervention in complex in vitro models
2025Open Access
Can we cure antiphospholipid syndrome?
Current Opinion in Immunology·2025· 1 cited
Advanced human iPSC-based modelling of <i>LMNA</i> -related congenital muscular dystrophy enables development of targeted genetic therapies for muscle laminopathies
2025Open Access
VISIBLE: An imaging-driven system for sampling, biofabrication, and manipulation of complex biological models
2025· 1 cited
PATIENTS WITH CARDIAC CHANNOLOPATHIES AT THE CARDIOLOGY DIVISION OF BOLZANO
European Heart Journal Supplements·2025
Metabolic remodeling in hiPSC-derived myofibers carrying the m.3243A&gt;G mutation
Stem Cell Reports·2025· 1 citedOpen Access
Efficacy of complement inhibition with pegcetacoplan in children with C3 glomerulopathy
Pediatric Nephrology·2025· 7 cited
Generation of a human induced pluripotent stem cell line (CRICKi021-A) from a patient with Ullrich congenital muscular dystrophy carrying a pathogenic mutation in the COL6A1 gene
Stem Cell Research·2024· 1 citedOpen Access
Antimicrobial Activity of Chitosan from Different Sources Against Non-Saccharomyces Wine Yeasts as a Tool for Producing Low-Sulphite Wine
Beverages·2024· 3 citedOpen Access
Ammonia transporter RhBG initiates downstream signaling and functional responses by activating NFκB
Proceedings of the National Academy of Sciences·2024· 3 citedOpen Access
Culturable yeast community associated with grape must and honey bees sampled from apiaries located in the vineyards
Journal of Applied Microbiology·2024
Metabolic remodelling in hiPSC-derived myofibres carrying the m.3243A&gt;G mutation
2024Open Access
Low-cost, versatile, and highly reproducible microfabrication pipeline to generate 3D-printed customised cell culture devices with complex designs
PLoS Biology·2024· 12 citedOpen Access
CRISPR-Cas9 mediated endogenous utrophin upregulation improves Duchenne Muscular Dystrophy
2023Open Access
Generation of an MTM1-mutant iPSC line (CRICKi008-A) from an individual with X-linked myotubular myopathy (XLMTM)
Stem Cell Research·2023· 1 citedOpen Access
3D human induced pluripotent stem cell–derived bioengineered skeletal muscles for tissue, disease and therapy modeling
Nature Protocols·2023· 50 citedOpen Access
Mesoangioblasts at 20: From the embryonic aorta to the patient bed
Frontiers in Genetics·2023· 10 citedOpen Access
High plasma C5a and C5b-9 levels during quiescent phases are associated to severe antiphospholipid syndrome subsets.
PubMed·2022· 5 cited
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Frequent Co-authors

Giulio Cossu(20), Sara Benedetti(13), Giuliana Ferrari(8), Rossana Tonlorenzi(8), Sara M. Maffioletti(7), Louise A. Moyle(7), Martina Ragazzi(7), M Gerli(7), Graziella Messina(6), Yvan Torrente(6), Sumitava Dastidar(5), Luca Pinton(4), Peter S. Zammit(4), Stefania Antonini(4), Hidetoshi Hoshiya(4), Mitsuo Oshimura(4), Maddalena Noviello(4), Thierry VandenDriessche(4), Arianna Dellavalle(3), Jordi Díaz‐Manera(3)