Carole Gwizdek

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index1.5kcitations33works1.02yr avg
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Research Topics

Ubiquitin and proteasome pathways(14), RNA Research and Splicing(13), RNA modifications and cancer(9), Genetics and Neurodevelopmental Disorders(9), Nuclear Structure and Function(6)

Publications33 total

How close are we to a cAMP- and cGMP-theory-based pharmacological therapy for fragile X syndrome?
Cell Reports Medicine·2025· 2 citedOpen Access
Fragile X Syndrome : identification of a new drug candidate
Neuroscience Applied·2025Open Access
Combining affinity purification and mass spectrometry to define the network of the nuclear proteins interacting with the N-terminal region of FMRP
Frontiers in Molecular Biosciences·2022· 10 citedOpen Access
Proteomics datasets of developing rat brain: Synaptic proteome and SUMO2/3-ylome
Data in Brief·2022· 2 citedOpen Access
Proteomic Identification of an Endogenous Synaptic SUMOylome in the Developing Rat Brain
Frontiers in Molecular Neuroscience·2021· 12 citedOpen Access
Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice
Nature Communications·2021· 38 citedOpen Access
Editorial: “Role of Ribonucleoprotein Complexes in Neurodevelopment and in the Physiopathology of Neurological Diseases”
Frontiers in Molecular Biosciences·2021Open Access
Abnormal AMPAR-mediated synaptic plasticity, cognitive and autistic-like behaviors in a missense <i>Fmr1</i> mutant mouse model of Fragile X syndrome
2020Open Access
The synaptic balance between sumoylation and desumoylation is maintained by the activation of metabotropic mGlu5 receptors
Cellular and Molecular Life Sciences·2019· 20 citedOpen Access
Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation
Nature Communications·2018· 69 citedOpen Access
Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein
eLife·2017· 41 citedOpen Access
Author response: Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein
2017· 2 citedOpen Access
mGlu5 receptors regulate synaptic sumoylation via a transient PKC-dependent diffusional trapping of Ubc9 into spines
Nature Communications·2014· 27 citedOpen Access
Protein Sumoylation in Brain Development, Neuronal Morphology and Spinogenesis
NeuroMolecular Medicine·2013· 29 cited
Activity‐dependent regulation of the sumoylation machinery in rat hippocampal neurons
Biology of the Cell·2012· 56 citedOpen Access
Developmental Regulation and Spatiotemporal Redistribution of the Sumoylation Machinery in the Rat Central Nervous System
PLoS ONE·2012· 52 citedOpen Access
H2B Ubiquitylation Controls the Formation of Export-Competent mRNP
Molecular Cell·2012· 54 citedOpen Access
Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels
Nature Structural & Molecular Biology·2011· 96 citedOpen Access
Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export
Genes & Development·2010· 159 citedOpen Access
Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation
Nature Cell Biology·2008· 109 cited
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Frequent Co-authors

Catherine Dargemont(13), Gwénola Poupon(11), Stéphane Martin(10), Marie Pronot(7), Barbara Bardoni(7), Anouar Khayachi(6), Batool Ossareh‐Nazari(5), Maria Hobeika(5), Nahid Iglesias(4), Françoise Stutz(4), Magda Chafaï(4), Frédéric Cassé(4), Marta Curto Prieto(4), Alessandra Folci(4), Céline Loriol(4), Emmanuel Deval(4), Paula A. Pousinha(4), Alain Doglio(3), Édouard Bertrand(3), Manuel S. Rodríguez(3)