Ollivier Hyrien

Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa — South Africa

Mathematics · Physical Sciences

29h-index3.2kcitations158works7.92yr avg
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Research Topics

Stochastic processes and statistical mechanics(20), HIV Research and Treatment(19), SARS-CoV-2 and COVID-19 Research(17), Immune Cell Function and Interaction(15), COVID-19 Clinical Research Studies(14)

Publications158 total

Immune correlates analysis of antibody responses against SARS-CoV-2 variants in the ENSEMBLE vaccine efficacy trial
iScience·2025Open Access
Safety and immunogenicity of investigational herpes simplex virus-2 vaccines in adults with recurrent genital infection
Vaccine·2025
Corrigendum to ‘Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study’. EBioMedicine 2024;108: 105320
EBioMedicine·2025Open Access
Priming VRC01-precursor B cells with non-envelope immunogens disfavors boosting with HIV-1 envelope
npj Vaccines·2025Open Access
Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial
Science Translational Medicine·2025· 13 citedOpen Access
Dose finding in early-phase human immunodeficiency virus type 1 prevention monoclonal antibody clinical trials
Clinical Trials·2025Open Access
High resolution class I HLA-A, -B, and -C diversity in Eastern and Southern African populations
Scientific Reports·2025· 5 citedOpen Access
Fixed dosing versus weight-based dosing of HIV-1 prophylactic monoclonal antibodies in adults: a post-hoc, cross-protocol pharmacokinetics modelling study
EBioMedicine·2025Open Access
Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa
Frontiers in Reproductive Health·2025Open Access
Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans
Science·2025· 30 citedOpen Access
Precise targeting of HIV broadly neutralizing antibody precursors in humans
Science·2025· 22 citedOpen Access
Distinct immune responses in people living with HIV following SARS-CoV-2 recovery
UNC Libraries·2025Open Access
Distinct immune responses in people living with HIV following SARS-CoV-2 recovery
Communications Medicine·2025· 1 citedOpen Access
Pharmacokinetic interaction assessment of an HIV broadly neutralizing monoclonal antibody VRC07-523LS: a cross-protocol analysis of three phase 1 trials in people without HIV
UNC Libraries·2025Open Access
Pharmacokinetic interaction assessment of an HIV broadly neutralizing monoclonal antibody VRC07-523LS: a cross-protocol analysis of three phase 1 trials in people without HIV
BMC Immunology·2025· 3 citedOpen Access
homeRNA self-blood collection enables high-frequency temporal profiling of presymptomatic host immune kinetics to respiratory viral infection: a prospective cohort study
EBioMedicine·2025· 5 citedOpen Access
Fixed Dosing Versus Weight-Based Dosing of HIV-1 Prophylactic Monoclonal Antibodies in Adults: A Pharmacokinetics Modeling Study
SSRN Electronic Journal·2025Open Access
Neutralizing antibody correlate of protection against severe-critical COVID-19 in the ENSEMBLE single-dose Ad26.COV2.S vaccine efficacy trial
Nature Communications·2024· 15 citedOpen Access
Use of 3M-052-AF with Alum adjuvant in HIV trimer vaccine induces human autologous neutralizing antibodies
The Journal of Experimental Medicine·2024· 15 citedOpen Access
Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study
EBioMedicine·2024· 13 citedOpen Access
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Frequent Co-authors

Shannon P. Hilchey(7), Lawrence Corey(7), Peter B. Gilbert(7), Steven H. Bernstein(6), Adrian B. McDermott(6), Richard A. Koup(6), M. Juliana McElrath(6), Alex Luedtke(5), Yuhchyau Chen(5), James G. Kublin(5), Martin S. Zand(5), Kathleen M. Neuzil(4), Lindsay N. Carpp(4), David Benkeser(4), Marco Carone(4), Youyi Fong(4), Yunda Huang(4), Michal Juraska(4), An Vandebosch(4), Myron S. Cohen(4)