Shehzad Z. Sheikh

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index2.2kcitations111works1.02yr avg
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Research Topics

Inflammatory Bowel Disease(48), Immune Cell Function and Interaction(17), Helicobacter pylori-related gastroenterology studies(14), Microscopic Colitis(13), Genetic factors in colorectal cancer(10)

Publications110 total

Reference-guided Genome Assembly of Long Non-coding RNA Transcripts Reveals Target Genes Associated With Crohn’s Disease
2025Open Access
Myeloid Cell Adhesion Molecule 1 (CADM1) Promotes Proinflammatory Signaling in Human Inflammatory Bowel Diseases
Cellular and Molecular Gastroenterology and Hepatology·2025· 1 citedOpen Access
A machine learning approach identifies 5-ASA and ulcerative colitis as being linked with higher COVID-19 mortality in patients with IBD
UNC Libraries·2025Open Access
Chromatin profiling to identify biomarkers in inflammatory bowel diseases
Current Opinion in Gastroenterology·2025· 1 citedOpen Access
Mo1918: EXPRESSION QUANTITATIVE TRAIT LOCI IN COLON TISSUE FROM PATIENTS IDENTIFY UNIQUE TARGET GENES ASSOCIATED WITH IBD
Gastroenterology·2025
eQTL in diseased colon tissue identifies novel target genes associated with IBD
2024Open Access
eQTL in diseased colon tissue identifies novel target genes associated with IBD
2024Open Access
Linking gene expression to clinical outcomes in pediatric Crohn's disease using machine learning
UNC Libraries·2024Open Access
Crohn's Disease Differentially Affects Region-Specific Composition and Aerotolerance Profiles of Mucosally Adherent Bacteria
UNC Libraries·2024Open Access
Redefining the IBDs using genome-scale molecular phenotyping
UNC Libraries·2024Open Access
Biochemical and rheological analysis of human colonic culture mucus reveals similarity to gut mucus
UNC Libraries·2024Open Access
Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients With Crohn's Disease
UNC Libraries·2024Open Access
Intestinal epithelial cell barrier dysfunction and elevated Angiopoietin-like 4 identified in orally susceptible peanut allergy model
UNC Libraries·2024Open Access
Single-Cell Analysis Reveals Unexpected Cellular Changes and Transposon Expression Signatures in the Colonic Epithelium of Treatment-Naive Adult Crohn's Disease Patients
UNC Libraries·2024Open Access
Colonic epithelial miR-31 associates with the development of Crohn's phenotypes
UNC Libraries·2024· 2 citedOpen Access
CoVar: A generalizable machine learning approach to identify the coordinated regulators driving variational gene expression
PLoS Computational Biology·2024· 1 citedOpen Access
Aberrant miR-29 is a predictive feature of severe phenotypes in pediatric Crohn’s disease
JCI Insight·2024· 6 citedOpen Access
Cutting Edge: Hypoxia Sensing by the Histone Demethylase UTX (KDM6A) Limits Colitogenic CD4+ T Cells in Mucosal Inflammation
The Journal of Immunology·2024· 3 citedOpen Access
<i>TNF</i> promoter hypomethylation is associated with mucosal inflammation in IBD and anti-TNF response
2024Open Access
Linking gene expression to clinical outcomes in pediatric Crohn’s disease using machine learning
Scientific Reports·2024· 7 citedOpen Access
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Frequent Co-authors

Terrence S. Furey(21), Scott E. Plevy(13), Matthew R. Schaner(13), Erin C. Steinbach(12), Praveen Sethupathy(12), Taku Kobayashi(10), Hans Herfarth(10), R. Balfour Sartor(10), Katsuyoshi Matsuoka(9), Timothy S. Sadiq(9), Mark J. Koruda(9), Jonathan J. Hansen(9), Caroline Beasley(9), Benjamin P. Keith(8), Elisabeth A. Wolber(8), Millie D. Long(7), Kim L. Isaacs(7), Meaghan M. Kennedy Ng(7), Grace Lian(7), Edward L. Barnes(7)