Makoto Nishiyama

The University of Tokyo — Japan

Materials Science · Physical Sciences

58h-index11.7kcitations408works2.22yr avg
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Research Topics

Enzyme Structure and Function(95), Microbial Natural Products and Biosynthesis(57), Amino Acid Enzymes and Metabolism(45), Microbial Metabolic Engineering and Bioproduction(34), Plant biochemistry and biosynthesis(31)

Publications406 total

Orthogonal Biosynthesis of Pyrrolamides through Dehydration by a Pathway-Specific Glycoside Hydrolase-Like Enzyme in Gram-Positive Bacteria
Journal of the American Chemical Society·2026Open Access
Increased ʟ-glutamate production from gaseous nitrogen using Klebsiella pasteurii NG13 with modified citrate synthase
Applied Microbiology and Biotechnology·2025Open Access
Regulation of membrane protein activity by cyclopropane fatty acids in Escherichia coli lipid environment
Communications Biology·2025Open Access
Catalytic regulation of CoA transferase by an NAD <sup>+</sup> -sensing accessory protein and protein acetylation
2025
Evolution of lysine and arginine biosynthesis revealed by substrate specificity of lysine biosynthetic enzymes in <i>Thermus thermophilus</i>
FEBS Journal·2025Open Access
Increased L-glutamate production from aerial nitrogen using Klebsiella pasteurii with modified citrate synthase
2025Open Access
Author response for "Evolution of lysine and arginine biosynthesis revealed by substrate specificity of lysine biosynthetic enzymes in &lt;i&gt;Thermus thermophilus&lt;/i&gt;"
2025
Phosphorylation-mediated regulation of the NADPH-dependent glutamate dehydrogenase, SpGdh1, from Schizosaccharomyces pombe
Journal of Biological Chemistry·2025· 1 citedOpen Access
Catalysis-dependent condensation of citrate synthase involved in glutamate overproduction in Corynebacterium glutamicum
2025Open Access
Abstract 1494 Phosphorylation-mediated regulation of NADPH-dependent glutamate dehydrogenase, SpGdh1, from Schizosaccharomyces pombe
Journal of Biological Chemistry·2025Open Access
Mechanistic Characterization of Diterpene Synthase Pairs for Tricyclic Diterpenes from Cyanobacteria
Journal of the American Chemical Society·2025· 6 cited
Biosynthesis of the tetrahydroxynaphthalene-derived meroterpenoid furaquinocin <i>via</i> reductive deamination and intramolecular hydroalkoxylation of an alkene
Chemical Science·2025· 6 citedOpen Access
Crystal structure of a novel heterooligomeric aminotransferase from <i>Serratia</i> sp. <scp>ATCC</scp> 39006 provides insights into function
FEBS Letters·2024Open Access
Complete genome sequence of a nitrogen-fixing bacterium, <i>Klebsiella pasteurii</i> (formerly <i>Klebsiella oxytoca</i> ) NG13, a rice rhizosphere isolate
Microbiology Resource Announcements·2024· 2 citedOpen Access
<i>In vivo</i> and <i>in vitro</i> Reconstitution of Biosynthesis of <i>N</i>‐Prenylated Phenazines Revealing Diverse Phenazine‐Modifying Enzymes
ChemBioChem·2024Open Access
Author response for "Crystal structure of a novel heterooligomeric aminotransferase from &lt;i&gt;Serratia&lt;/i&gt; sp. &lt;scp&gt;ATCC&lt;/scp&gt; 39006 provides insights into function"
2024
Improvement of the nitrogenase activity in Escherichia coli that expresses the nitrogen fixation-related genes from Azotobacter vinelandii
Biochemical and Biophysical Research Communications·2024· 15 citedOpen Access
Glutamate production from aerial nitrogen using the nitrogen-fixing bacterium Klebsiella oxytoca
Communications Biology·2024· 12 citedOpen Access
Characterization of the &lt;i&gt;Azotobacter vinelandii&lt;/i&gt; nitrogenase complex expressed in &lt;i&gt;Escherichia coli&lt;/i&gt; toward further activity improvement
The Journal of General and Applied Microbiology·2024Open Access
Discovery of type II polyketide synthase-like enzymes for the biosynthesis of cispentacin
Nature Communications·2023· 10 citedOpen Access
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Frequent Co-authors

Sueharu Horinouchi(19), Teruhiko Beppu(10), Tomohisa Kuzuyama(7), Kyonsoo Hong(6), Toru Beppu(6), Minoru Yoshida(5), Mutsuko Kukimoto‐Niino(5), Hisakazu Yamane(5), Nobuyuki Kobashi(4), Elinor T. Adman(4), Chiharu Nishiyama(4), Takeo Tomita(4), Naoto Shibuya(4), Hideaki Nojiri(4), M.E.P. Murphy(3), S. Turley(3), Ayako Yoshida(3), Ryûichi Sawa(3), Eun‐Min Cho(3), Toshio Omori(3)