Kazuyuki Tomisawa

Fukuoka Institute of Health and Environmental Sciences — Japan

Neuroscience · Life Sciences

16h-index979citations85works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(16), Receptor Mechanisms and Signaling(14), Chemical Synthesis and Analysis(9), Neurotransmitter Receptor Influence on Behavior(8), Synthesis and biological activity(8)

Publications85 total

Analysis of Volatile Sulfur Compounds Secreted by Diving Beetle, <i>Cybister tripunctatus lateralis</i>
Journal of Japan Association on Odor Environment·2025Open Access
Study of Speciation Analysis Methods for Gd Contrast Agents by LC-ICP-MS Using an Ion Exchange Column
Journal of Environmental Chemistry·2025Open Access
Synthesis and structure–activity relationships of 5-phenylthiophenecarboxylic acid derivatives as antirheumatic agents
Bioorganic & Medicinal Chemistry·2003· 16 cited
A Practical Procedure for the Synthesis of Esonarimod, (R,S)‐2‐Acetylthiomethyl‐4‐(4‐methylphenyl)‐4‐oxobutanoic Acid, an Antirheumatic Agent. Part 1.
ChemInform·2003
Synthesis of Dihydrothiophene Derivatives as Metabolites of Esonarimod.
ChemInform·2003
Synthesis and Antirheumatic Activity of the Metabolites of Esonarimod
Bioorganic & Medicinal Chemistry·2002· 3 cited
Synthesis of Dihydrothiophene Derivatives as Metabolites of Esonarimod
Heterocycles·2002· 2 citedOpen Access
A Practical Procedure for the Synthesis of Esonarimod, (R,S)-2-Acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic Acid, an Antirheumatic Agent. (Part 1).
Chemical and Pharmaceutical Bulletin·2002· 10 citedOpen Access
Design, synthesis and structure–affinity relationships of 4-methylidenepiperidine and 4-aryl-1,2,3,6-tetrahydropyridine derivatives as corticotropin-releasing factor1 receptor antagonists
Bioorganic & Medicinal Chemistry·2000· 14 cited
Differential glycosylation of secretory and vacuolar glycoproteins in rice cell culture.
2000
Effects of selective dopamine D4 receptor blockers, NRA0160 and L-745,870, on A9 and A10 dopamine neurons in rats
Life Sciences·1999· 5 cited
Up-regulation of low density lipoprotein receptor by a novel isobenzofranone derivative, MD-700
Atherosclerosis·1999· 11 cited
A selective dopamine D4 receptor antagonist, NRA0160: A preclinical neuropharmacological profile
Life Sciences·1999· 28 cited
Synthesis and SAR of 1-Alkyl-2-phenylethylamine Derivatives Designed from<i>N</i>,<i>N</i>-Dipropyl-4-methoxy-3-(2-phenylethoxy)phenylethylamine To Discover σ<sub>1</sub>Ligands
Journal of Medicinal Chemistry·1999· 21 citedOpen Access
In vivo receptor occupancy of NRA0045, a putative atypical antipsychotic, in rats
Neuropharmacology·1999· 12 cited
Effects of NRA0045, NRA0160, and NRA0215 on regional Fos-like immunoreactivity in the rat brain
General Pharmacology The Vascular System·1999· 5 cited
Taurine improves serum cholesterol levels and retards the progression of atherosclerosis
Atherosclerosis·1999· 1 cited
Receptor Binding, Behavioral, and Electrophysiological Profiles of Nonpeptide Corticotropin-Releasing Factor Subtype 1 Receptor Antagonists CRA1000 and CRA1001
Journal of Pharmacology and Experimental Therapeutics·1999· 153 citedOpen Access
In vitro pharmacological profile of nonpeptide CRF1 receptor antagonists, CRA1000 and CRA1001
European Journal of Pharmacology·1999· 35 cited
Binding characteristics of DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors
European Journal of Pharmacology·1999· 80 cited
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Frequent Co-authors

Shigeru Okuyama(14), Atsuro Nakazato(12), Shigeyuki Chaki(11), Toshihito Kumagai(9), Kazuya Kameo(9), K. SOTA(9), Ryoko Yoshikawa(7), Naoya Kawashima(6), Shinichi Ogawa(6), Taketoshi Okubo(6), Shigeru Murakami(6), Yumiko Asami(6), Yoshiko Suzuki(5), Takeo Funakoshi(5), Toshihisa Ogawa(5), Masashi Nagamine(4), Kimiyo Takeshita(4), Masakazu Sato(4), Toshiya Noguchi(4), Shigeyuki Chaki(3)