Nancy Leymarie

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.5kcitations35works0.02yr avg
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Research Topics

Glycosylation and Glycoproteins Research(18), Mass Spectrometry Techniques and Applications(9), Advanced Proteomics Techniques and Applications(8), Proteoglycans and glycosaminoglycans research(8), Carbohydrate Chemistry and Synthesis(5)

Publications35 total

Systematic cysteine scanning identifies a druggable pocket in oncogenic KRAS
Cell chemical biology·2026
Targeting NEDD9-SH3 with a Covalent Peptide Controls Endothelial Phenotype
2025Open Access
A Phase <scp>1B</scp> Trial in <i><scp>GBA1</scp>‐</i>Associated Parkinson's Disease of BIA‐28‐6156, a Glucocerebrosidase Activator
Movement Disorders·2023· 33 citedOpen Access
Abstract B037: Hit-finding by Cysteine-Scanning (HCS): A method for finding druggable pockets
Molecular Cancer Research·2023
A Biomarker Study in Patients with <i>GBA1</i>‐Parkinson's Disease and Healthy Controls
Movement Disorders·2023· 24 citedOpen Access
Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus
Journal of Biological Chemistry·2018· 20 citedOpen Access
Structure of N-glycosylated porcine surfactant protein-D complexed with glycerol
2017
Integrated Omics and Computational Glycobiology Reveal Structural Basis for Influenza A Virus Glycan Microheterogeneity and Host Interactions
Molecular & Cellular Proteomics·2016· 99 citedOpen Access
A review of methods for interpretation of glycopeptide tandem mass spectral data
Glycoconjugate Journal·2015· 90 citedOpen Access
Workflow for Combined Proteomics and Glycomics Profiling from Histological Tissues
Analytical Chemistry·2014· 49 citedOpen Access
Confident Assignment of Site-Specific Glycosylation in Complex Glycoproteins in a Single Step
Journal of Proteome Research·2014· 47 citedOpen Access
Detecting O-GlcNAc using in vitro sulfation
Glycobiology·2014· 11 citedOpen Access
Detecting O‐GlcNAc using in vitro sulfation (607.1)
The FASEB Journal·2014
Top‐down tandem mass spectrometry on <scp>RN</scp>ase <scp>A</scp> and <scp>B</scp> using a <scp>Q</scp>h/<scp>FT</scp>‐<scp>ICR</scp> hybrid mass spectrometer
PROTEOMICS·2014· 37 citedOpen Access
Direct Detection of <i>S</i>-Palmitoylation by Mass Spectrometry
Analytical Chemistry·2013· 85 citedOpen Access
Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: The ABRF Glycoprotein Research Multi-Institutional Study 2012
Molecular & Cellular Proteomics·2013· 113 citedOpen Access
Glycoprotein Research Group (gPRG) 2013 Interlaboratory Study: Quantitative N-glycan Profiling of Prostate Specific Antigen
Europe PMC (PubMed Central)·2013Open Access
Effective Use of Mass Spectrometry for Glycan and Glycopeptide Structural Analysis
Analytical Chemistry·2012· 186 citedOpen Access
gPRG) 2012 Quantitative Glycoprotein Study
Europe PMC (PubMed Central)·2012Open Access
A Typical Preparation of <i>Francisella tularensis</i><i>O</i>-Antigen Yields a Mixture of Three Types of Saccharides
Biochemistry·2011· 25 citedOpen Access
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Frequent Co-authors

Joseph Zaia(22), Catherine E. Costello(8), Kshitij Khatri(8), Gregory O. Staples(6), Hicham Naimy(6), Mark E. McComb(5), Kevan L. Hartshorn(5), Mitchell R. White(4), Michael J. Rynkiewicz(4), Barbara A. Seaton(4), Daniel Kolarich(3), Ron Orlando(3), Martin van Eijk(3), Peter B. O’Connor(2), John F. Cipollo(2), Detlev Suckau(2), Morten Thaysen‐Andersen(2), Michael J. Bowman(2), Xiaofeng Shi(2), Joshua Klein(2)