Ruiqian Wan

National Institute on Aging — United States

Medicine · Health Sciences

33h-index5.2kcitations48works0.02yr avg
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Research Topics

Adipose Tissue and Metabolism(14), Stress Responses and Cortisol(11), Dietary Effects on Health(11), Neuroscience and Neuropharmacology Research(7), Genetics, Aging, and Longevity in Model Organisms(7)

Publications48 total

Mitochondrial SIRT3 Deficiency Results in Neuronal Network Hyperexcitability, Accelerates Age-Related Aβ Pathology, and Renders Neurons Vulnerable to Aβ Toxicity
NeuroMolecular Medicine·2022· 12 citedOpen Access
SIRT3 Haploinsufficiency Aggravates Loss of GABAergic Interneurons and Neuronal Network Hyperexcitability in an Alzheimer's Disease Model
Journal of Neuroscience·2019· 96 citedOpen Access
SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice
Nature Communications·2019· 165 citedOpen Access
Adenosine receptors as markers of brain iron deficiency: Implications for Restless Legs Syndrome
Neuropharmacology·2016· 60 citedOpen Access
Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges
Cell Metabolism·2015· 368 citedOpen Access
Evidence that <scp>BDNF</scp> regulates heart rate by a mechanism involving increased brainstem parasympathetic neuron excitability
Journal of Neurochemistry·2014· 83 citedOpen Access
Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1−42 on neural progenitor cell proliferation
Neurobiology of Aging·2013· 62 cited
Toll-like receptors 2 and 4 modulate autonomic control of heart rate and energy metabolism
Brain Behavior and Immunity·2013· 50 citedOpen Access
Testing the product of slopes in related regressions.
PubMed·2013Open Access
A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease
Neurobiology of Aging·2012· 351 citedOpen Access
Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines
Nature Communications·2012· 388 citedOpen Access
Mitochondrial Superoxide Production Negatively Regulates Neural Progenitor Proliferation and Cerebral Cortical Development
Stem Cells·2012· 88 citedOpen Access
Dietary energy intake modifies brainstem autonomic dysfunction caused by mutant α-synuclein
Neurobiology of Aging·2012· 68 citedOpen Access
Brain‐derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health
Annals of the New York Academy of Sciences·2012· 182 citedOpen Access
Neuroprotection provided by dietary restriction in rats is further enhanced by reducing glucocortocoids
Neurobiology of Aging·2012· 38 citedOpen Access
Aberrant heart rate and brainstem brain-derived neurotrophic factor (BDNF) signaling in a mouse model of Huntington's disease
Neurobiology of Aging·2011· 32 citedOpen Access
Adiponectin protects rat hippocampal neurons against excitotoxicity
AGE·2010· 78 citedOpen Access
GLP-1 receptor stimulation depresses heart rate variability and inhibits neurotransmission to cardiac vagal neurons
Cardiovascular Research·2010· 101 citedOpen Access
Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis
Proceedings of the National Academy of Sciences·2010· 210 citedOpen Access
Chronic Alternate-Day Fasting Results in Reduced Diastolic Compliance and Diminished Systolic Reserve in Rats
Journal of Cardiac Failure·2010· 33 citedOpen Access
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Frequent Co-authors

Mark P. Mattson(37), Aiwu Cheng(12), Eitan Okun(7), Kathleen J. Griffioen(7), Ismayil Ahmet(5), Mark I. Talan(5), Xin Ouyang(4), Mohamed R. Mughal(4), Thiruma V. Arumugam(4), Terry M. Phillips(4), Edward G. Lakatta(4), Simonetta Camandola(4), Christopher H. Morrell(3), Sarah M. Rothman(3), David S. Olton(3), Wybren de Jong(3), D. de Wied(3), Naomi Kamimura(2), Ying Yang(2), Daoyuan Lu(2)